Translation initiation factor eIF4G1 preferentially binds yeast transcript leaders containing conserved oligo-uridine motifs.

Zinshteyn, Boris; Rojas-Duran, Maria F; Gilbert, Wendy V

Zinshteyn, Boris; Rojas-Duran, Maria F; Gilbert, Wendy V.

Affiliation

Zinshteyn B; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Rojas-Duran MF; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Gilbert WV; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

RNA ; 23(9): 1365-1375, 2017 09.

Article in En | MEDLINE | ID: mdl-28546148

Subject(s)

Binding Sites; Eukaryotic Initiation Factor-4G/metabolism; Gene Expression Regulation, Fungal; Nucleotide Motifs; Poly U/metabolism; RNA, Messenger/genetics; RNA, Messenger/metabolism; Conserved Sequence; Protein Binding; Protein Biosynthesis; RNA, Messenger/chemistry; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae/metabolism

Key words

RNA binding; eIF4G; ribosome footprint profiling; transcript leaders; translation initiation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Poly U / Binding Sites / RNA, Messenger / Gene Expression Regulation, Fungal / Eukaryotic Initiation Factor-4G / Nucleotide Motifs Type of study: Prognostic_studies Language: En Journal: RNA Journal subject: BIOLOGIA MOLECULAR Year: 2017 Type: Article Affiliation country: United States

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