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SUMO Teams Up with a Translocase to Save TOPO.
Dhingra, Nalini; Zhao, Xiaolan.
Affiliation
  • Dhingra N; Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Zhao X; Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: zhaox1@mskcc.org.
Mol Cell ; 66(5): 577-578, 2017 Jun 01.
Article in En | MEDLINE | ID: mdl-28575654
ABSTRACT
In this issue of Molecular Cell, Wei et al. (2017) report how a DNA translocase uses SUMO as a cue to save Top2 from ubiquitin-mediated degradation and to minimize DNA breaks, thus providing insights into the SUMO and ubiquitin interplay in genome maintenance.
Subject(s)
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: SUMO-1 Protein / Sumoylation Limits: Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2017 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: SUMO-1 Protein / Sumoylation Limits: Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2017 Type: Article Affiliation country: United States