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CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion.
Mou, Haiwei; Smith, Jordan L; Peng, Lingtao; Yin, Hao; Moore, Jill; Zhang, Xiao-Ou; Song, Chun-Qing; Sheel, Ankur; Wu, Qiongqiong; Ozata, Deniz M; Li, Yingxiang; Anderson, Daniel G; Emerson, Charles P; Sontheimer, Erik J; Moore, Melissa J; Weng, Zhiping; Xue, Wen.
Affiliation
  • Mou H; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
  • Smith JL; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
  • Peng L; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
  • Yin H; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA.
  • Moore J; Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
  • Zhang XO; Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
  • Song CQ; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
  • Sheel A; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
  • Wu Q; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA.
  • Ozata DM; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
  • Li Y; Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
  • Anderson DG; Department of Bioinformatics, School of Life Science and Technology, Tongji University, Shanghai, People's Republic of China.
  • Emerson CP; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA.
  • Sontheimer EJ; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA.
  • Moore MJ; Harvard-MIT Division of Health Sciences & Technology, Cambridge, MA, 02139, USA.
  • Weng Z; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Xue W; Wellstone Muscular Dystrophy Program, Department of Neurology, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
Genome Biol ; 18(1): 108, 2017 06 14.
Article in En | MEDLINE | ID: mdl-28615073
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genome, Human / Exons / CRISPR-Cas Systems / Gene Editing Limits: Humans Language: En Journal: Genome Biol Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2017 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genome, Human / Exons / CRISPR-Cas Systems / Gene Editing Limits: Humans Language: En Journal: Genome Biol Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2017 Type: Article Affiliation country: United States