The microglial fractalkine receptor is not required for activity-dependent plasticity in the mouse visual system.

Lowery, Rebecca L; Tremblay, Marie-Eve; Hopkins, Brittany E; Majewska, Ania K

Lowery, Rebecca L; Tremblay, Marie-Eve; Hopkins, Brittany E; Majewska, Ania K.

Affiliation

Lowery RL; Neuroscience Graduate Program, University of Rochester, Rochester, New York, 14642.
Tremblay ME; Department of Neuroscience, Center for Visual Science, University of Rochester, Rochester, New York, 14642.
Hopkins BE; Department of Neuroscience, Center for Visual Science, University of Rochester, Rochester, New York, 14642.
Majewska AK; Department of Molecular Medicine, Université Laval, and Axe Neurosciences, Centre De Recherche Du CHU De Québec, Québec City, Canada.

Glia ; 65(11): 1744-1761, 2017 11.

Article in En | MEDLINE | ID: mdl-28836393

Subject(s)

CX3C Chemokine Receptor 1/metabolism; Gene Expression Regulation, Developmental/genetics; Microglia/physiology; Neuronal Plasticity/physiology; Sensory Deprivation/physiology; Visual Pathways/cytology; Age Factors; Animals; Animals, Newborn; Antibodies/administration & dosage; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; CX3C Chemokine Receptor 1/genetics; CX3C Chemokine Receptor 1/immunology; Chemokine CX3CL1/metabolism; Dendritic Spines/ultrastructure; Green Fluorescent Proteins/genetics; Green Fluorescent Proteins/metabolism; Luminescent Proteins/genetics; Luminescent Proteins/metabolism; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia/drug effects; Neuronal Plasticity/drug effects; Neuronal Plasticity/genetics; Neurons/ultrastructure; Signal Transduction/physiology; Visual Cortex/cytology; Visual Cortex/growth & development; Visual Cortex/metabolism; Visual Pathways/drug effects; Visual Pathways/growth & development

Key words

CX3CR1; lateral geniculate nucleus; synaptic plasticity; visual cortex

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sensory Deprivation / Visual Pathways / Microglia / Gene Expression Regulation, Developmental / CX3C Chemokine Receptor 1 / Neuronal Plasticity Limits: Animals Language: En Journal: Glia Journal subject: NEUROLOGIA Year: 2017 Type: Article

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