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Liver cyst gene knockout in cholangiocytes inhibits cilium formation and Wnt signaling.
Wills, Edgar S; Te Morsche, René H M; van Reeuwijk, Jeroen; Horn, Nicola; Geomini, Iris; van de Laarschot, Liyanne F M; Mans, Dorus A; Ueffing, Marius; Boldt, Karsten; Drenth, Joost P H; Roepman, Ronald.
Affiliation
  • Wills ES; Department of Gastroenterology and Hepatology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
  • Te Morsche RHM; Department of Gastroenterology and Hepatology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
  • van Reeuwijk J; Department of Human Genetics and Radboud Insitute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
  • Horn N; Division of Experimental Ophthalmology and Medical Bioanalytics, Center for Ophthalmology, Eberhard-Karls University Tübingen, 72076, Tübingen, Germany.
  • Geomini I; Department of Gastroenterology and Hepatology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
  • van de Laarschot LFM; Department of Gastroenterology and Hepatology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
  • Mans DA; Department of Human Genetics and Radboud Insitute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
  • Ueffing M; Division of Experimental Ophthalmology and Medical Bioanalytics, Center for Ophthalmology, Eberhard-Karls University Tübingen, 72076, Tübingen, Germany.
  • Boldt K; Division of Experimental Ophthalmology and Medical Bioanalytics, Center for Ophthalmology, Eberhard-Karls University Tübingen, 72076, Tübingen, Germany.
  • Drenth JPH; Department of Gastroenterology and Hepatology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
  • Roepman R; Department of Human Genetics and Radboud Insitute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Hum Mol Genet ; 26(21): 4190-4202, 2017 11 01.
Article in En | MEDLINE | ID: mdl-28973524
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cilia / Cysts / Intracellular Signaling Peptides and Proteins / Glucosidases / Liver Diseases / Membrane Proteins Limits: Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2017 Type: Article Affiliation country: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cilia / Cysts / Intracellular Signaling Peptides and Proteins / Glucosidases / Liver Diseases / Membrane Proteins Limits: Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2017 Type: Article Affiliation country: Netherlands