IL-17 Activates the IL-6/STAT3 Signal Pathway in the Proliferation of Hepatitis B Virus-Related Hepatocellular Carcinoma.

Hu, Zongqiang; Luo, Ding; Wang, Dongdong; Ma, Linjie; Zhao, Yingpeng; Li, Li

Hu, Zongqiang; Luo, Ding; Wang, Dongdong; Ma, Linjie; Zhao, Yingpeng; Li, Li.

Cell Physiol Biochem ; 43(6): 2379-2390, 2017.

Article in En | MEDLINE | ID: mdl-29073625

Subject(s)

Cell Proliferation/drug effects; Interleukin-17/pharmacology; Interleukin-6/immunology; STAT3 Transcription Factor/metabolism; Signal Transduction/drug effects; Animals; Antibodies, Neutralizing/immunology; Antibodies, Neutralizing/pharmacology; Carcinoma, Hepatocellular/etiology; Carcinoma, Hepatocellular/metabolism; Carcinoma, Hepatocellular/pathology; Cell Movement/drug effects; Chemokine CCL2/analysis; Chemokine CCL5/analysis; Disease Models, Animal; Female; Hep G2 Cells; Hepatitis B/complications; Hepatitis B/pathology; Hepatitis B/virology; Hepatitis B virus/physiology; Humans; Interleukin-17/genetics; Interleukin-17/metabolism; Interleukin-6/analysis; Liver Neoplasms/etiology; Liver Neoplasms/metabolism; Liver Neoplasms/pathology; Mice; Mice, Inbred BALB C; Mice, Knockout; Microscopy, Fluorescence; Phosphorylation/drug effects; Recombinant Proteins/biosynthesis; Recombinant Proteins/genetics; Recombinant Proteins/pharmacology; STAT3 Transcription Factor/antagonists & inhibitors; Transplantation, Heterologous; Vascular Endothelial Growth Factor A/analysis

Key words

HBV; HCC; IL-17; IL-6; pSTAT3

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Interleukin-6 / Interleukin-17 / Cell Proliferation / STAT3 Transcription Factor Type of study: Etiology_studies / Prognostic_studies Language: En Journal: Cell Physiol Biochem Journal subject: BIOQUIMICA / FARMACOLOGIA Year: 2017 Type: Article

Fulltext

XML

PubMed Links

Search on Google