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Canine Hepatitis Associated with Intrahepatic Bacteria in Three Dogs.
Im, Joon; Burney, Derek P; McDonough, Sean P; Nicholson, Brigid; Eatroff, Adam; Simpson, Kenneth W.
Affiliation
  • Im J; From the Blue Pearl Veterinary Partners, New York, New York (J.I., A.E.); Veterinary Specialists of North Texas, Dallas, Texas (D.P.B.); College of Veterinary Medicine, Cornell University, Ithaca, New York (S.P.M., K.W.S.); and SAGE Centers for Veterinary Specialty and Emergency Care, Campbell, Cali
  • Burney DP; From the Blue Pearl Veterinary Partners, New York, New York (J.I., A.E.); Veterinary Specialists of North Texas, Dallas, Texas (D.P.B.); College of Veterinary Medicine, Cornell University, Ithaca, New York (S.P.M., K.W.S.); and SAGE Centers for Veterinary Specialty and Emergency Care, Campbell, Cali
  • McDonough SP; From the Blue Pearl Veterinary Partners, New York, New York (J.I., A.E.); Veterinary Specialists of North Texas, Dallas, Texas (D.P.B.); College of Veterinary Medicine, Cornell University, Ithaca, New York (S.P.M., K.W.S.); and SAGE Centers for Veterinary Specialty and Emergency Care, Campbell, Cali
  • Nicholson B; From the Blue Pearl Veterinary Partners, New York, New York (J.I., A.E.); Veterinary Specialists of North Texas, Dallas, Texas (D.P.B.); College of Veterinary Medicine, Cornell University, Ithaca, New York (S.P.M., K.W.S.); and SAGE Centers for Veterinary Specialty and Emergency Care, Campbell, Cali
  • Eatroff A; From the Blue Pearl Veterinary Partners, New York, New York (J.I., A.E.); Veterinary Specialists of North Texas, Dallas, Texas (D.P.B.); College of Veterinary Medicine, Cornell University, Ithaca, New York (S.P.M., K.W.S.); and SAGE Centers for Veterinary Specialty and Emergency Care, Campbell, Cali
  • Simpson KW; From the Blue Pearl Veterinary Partners, New York, New York (J.I., A.E.); Veterinary Specialists of North Texas, Dallas, Texas (D.P.B.); College of Veterinary Medicine, Cornell University, Ithaca, New York (S.P.M., K.W.S.); and SAGE Centers for Veterinary Specialty and Emergency Care, Campbell, Cali
J Am Anim Hosp Assoc ; 54(1): 65-70, 2018.
Article in En | MEDLINE | ID: mdl-29131670
ABSTRACT
This case report describes the detection of intrahepatic bacteria in formalin-fixed paraffin-embedded histopathological sections from three dogs with neutrophilic, pyogranulomatous, or lymphoplasmacytic hepatitis and cholangiohepatitis. In each of these cases, eubacterial fluorescence in situ hybridization enabled colocalization of intrahepatic bacteria with neutrophilic and granulomatous inflammation in samples that were negative for bacteria when evaluated by routine hematoxylin and eosin histopathology augmented with histochemical stains. Positive responses to antimicrobial therapy were observed in of 2 out of 2 patients that were treated with antimicrobials. These findings suggest that eubacterial fluorescence in situ hybridization analysis of formalin-fixed paraffin-embedded histopathological sections is more sensitive than conventional histochemical stains for the diagnosis of bacteria-associated canine hepatitis.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacteria / In Situ Hybridization, Fluorescence / Dog Diseases / Hepatitis, Animal Type of study: Risk_factors_studies Limits: Animals Language: En Journal: J Am Anim Hosp Assoc Year: 2018 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacteria / In Situ Hybridization, Fluorescence / Dog Diseases / Hepatitis, Animal Type of study: Risk_factors_studies Limits: Animals Language: En Journal: J Am Anim Hosp Assoc Year: 2018 Type: Article