Expression of Telomere-Associated Proteins is Interdependent to Stabilize Native Telomere Structure and Telomere Dysfunction by G-Quadruplex Ligand Causes TERRA Upregulation.

Sadhukhan, Ratan; Chowdhury, Priyanka; Ghosh, Sourav; Ghosh, Utpal

Sadhukhan, Ratan; Chowdhury, Priyanka; Ghosh, Sourav; Ghosh, Utpal.

Affiliation

Sadhukhan R; Department of Biochemistry & Biophysics, University of Kalyani, Kalyani, 741235, India.
Chowdhury P; Department of Biochemistry & Biophysics, University of Kalyani, Kalyani, 741235, India.
Ghosh S; Department of Biochemistry & Biophysics, University of Kalyani, Kalyani, 741235, India.
Ghosh U; Department of Biochemistry & Biophysics, University of Kalyani, Kalyani, 741235, India. utpal8ghosh@gmail.com.

Cell Biochem Biophys ; 76(1-2): 311-319, 2018 Jun.

Article in En | MEDLINE | ID: mdl-29134494

Subject(s)

RNA, Long Noncoding/metabolism; Telomere/metabolism; Telomeric Repeat Binding Protein 1/metabolism; Telomeric Repeat Binding Protein 2/metabolism; A549 Cells; Bleomycin/pharmacology; G-Quadruplexes; Humans; In Situ Hybridization, Fluorescence; Microscopy, Fluorescence; Poly (ADP-Ribose) Polymerase-1/antagonists & inhibitors; Poly (ADP-Ribose) Polymerase-1/genetics; Poly (ADP-Ribose) Polymerase-1/metabolism; RNA Interference; RNA, Long Noncoding/genetics; RNA, Small Interfering/metabolism; Recombinases/antagonists & inhibitors; Recombinases/genetics; Recombinases/metabolism; Telomere/chemistry; Telomeric Repeat Binding Protein 1/antagonists & inhibitors; Telomeric Repeat Binding Protein 1/genetics; Telomeric Repeat Binding Protein 2/antagonists & inhibitors; Telomeric Repeat Binding Protein 2/genetics; Up-Regulation/drug effects

Key words

Bleomycin; G-quadruplex ligand; PARP-1; Pyridostatin; TERRA; Telomere

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Telomere / Telomeric Repeat Binding Protein 1 / Telomeric Repeat Binding Protein 2 / RNA, Long Noncoding Type of study: Etiology_studies / Risk_factors_studies Limits: Humans Language: En Journal: Cell Biochem Biophys Journal subject: BIOFISICA / BIOQUIMICA Year: 2018 Type: Article Affiliation country: India

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