Development of Multigenic Lentiviral Vectors for Cell-Specific Expression of Antiangiogenic miRNAs and Protein Factors.

Askou, Anne Louise; Corydon, Thomas J

Askou, Anne Louise; Corydon, Thomas J.

Affiliation

Askou AL; Department of Biomedicine, Aarhus University, Aarhus C, Denmark.
Corydon TJ; Department of Biomedicine, Aarhus University, Aarhus C, Denmark. corydon@biomed.au.dk.

Methods Mol Biol ; 1715: 47-60, 2018.

Article in En | MEDLINE | ID: mdl-29188505

Subject(s)

Angiogenesis Inhibitors/administration & dosage; Genetic Therapy/methods; Genetic Vectors; Lentivirus/genetics; Macular Degeneration/therapy; Retinal Neovascularization/therapy; Fluorescent Dyes/metabolism; Gene Transfer Techniques; Humans; Macular Degeneration/genetics; MicroRNAs/administration & dosage; MicroRNAs/genetics; MicroRNAs/metabolism; RNA Polymerase II/genetics; RNA Polymerase II/metabolism; Retinal Neovascularization/genetics

Key words

AMD; Antiangiogenesis; Cell-specific expression; Coexpression; DNA cloning; Lentivirus; Multigenic vector; Retina; VEGF; miRNA

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Therapy / Retinal Neovascularization / Lentivirus / Angiogenesis Inhibitors / Genetic Vectors / Macular Degeneration Limits: Humans Language: En Journal: Methods Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2018 Type: Article Affiliation country: Denmark

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