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The CC chemokine ligand (CCL) 1, upregulated by the viral transactivator Tax, can be downregulated by minocycline: possible implications for long-term treatment of HTLV-1-associated myelopathy/tropical spastic paraparesis.
Saito, Mineki; Sejima, Hiroe; Naito, Tadasuke; Ushirogawa, Hiroshi; Matsuzaki, Toshio; Matsuura, Eiji; Tanaka, Yuetsu; Nakamura, Tatsufumi; Takashima, Hiroshi.
Affiliation
  • Saito M; Department of Microbiology, Kawasaki Medical School, 577 Matsushima, Okayama, 701-0192, Japan. mineki@med.kawasaki-m.ac.jp.
  • Sejima H; Department of Microbiology, Kawasaki Medical School, 577 Matsushima, Okayama, 701-0192, Japan.
  • Naito T; Department of Microbiology, Kawasaki Medical School, 577 Matsushima, Okayama, 701-0192, Japan.
  • Ushirogawa H; Department of Microbiology, Kawasaki Medical School, 577 Matsushima, Okayama, 701-0192, Japan.
  • Matsuzaki T; Department of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8520, Japan.
  • Matsuura E; Department of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8520, Japan.
  • Tanaka Y; Department of Immunology, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Okinawa, 903-0215, Japan.
  • Nakamura T; Department of Social Work, Faculty of Human and Social Studies, Nagasaki International University, 2825-7 Huis Ten Bosch Machi, Sasebo, Nagasaki, 859-3298, Japan.
  • Takashima H; Department of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8520, Japan.
Virol J ; 14(1): 234, 2017 12 04.
Article in En | MEDLINE | ID: mdl-29202792

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Paraparesis, Tropical Spastic / Down-Regulation / Up-Regulation / Gene Products, tax / Chemokine CCL1 / Minocycline Type of study: Risk_factors_studies Limits: Adult / Humans Language: En Journal: Virol J Journal subject: VIROLOGIA Year: 2017 Type: Article Affiliation country: Japan

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Paraparesis, Tropical Spastic / Down-Regulation / Up-Regulation / Gene Products, tax / Chemokine CCL1 / Minocycline Type of study: Risk_factors_studies Limits: Adult / Humans Language: En Journal: Virol J Journal subject: VIROLOGIA Year: 2017 Type: Article Affiliation country: Japan