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In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation.
Liao, Hsin-Kai; Hatanaka, Fumiyuki; Araoka, Toshikazu; Reddy, Pradeep; Wu, Min-Zu; Sui, Yinghui; Yamauchi, Takayoshi; Sakurai, Masahiro; O'Keefe, David D; Núñez-Delicado, Estrella; Guillen, Pedro; Campistol, Josep M; Wu, Cheng-Jang; Lu, Li-Fan; Esteban, Concepcion Rodriguez; Izpisua Belmonte, Juan Carlos.
Affiliation
  • Liao HK; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Hatanaka F; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Araoka T; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Universidad Catolica, San Antonio de Murcia, Campus de los Jeronimos, 135, 30107 Guadalupe, Spain.
  • Reddy P; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Wu MZ; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Universidad Catolica, San Antonio de Murcia, Campus de los Jeronimos, 135, 30107 Guadalupe, Spain.
  • Sui Y; Department of Pediatrics and Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Yamauchi T; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Universidad Catolica, San Antonio de Murcia, Campus de los Jeronimos, 135, 30107 Guadalupe, Spain.
  • Sakurai M; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • O'Keefe DD; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Núñez-Delicado E; Universidad Catolica, San Antonio de Murcia, Campus de los Jeronimos, 135, 30107 Guadalupe, Spain.
  • Guillen P; Fundacion Pedro Guillen, Clinica CEMTRO, Avenida Ventisquero de la Condesa, 42, 28035 Madrid, Spain.
  • Campistol JM; Hospital Clinic of Barcelona, Carrer Villarroel, 170, 08036 Barcelona, Spain.
  • Wu CJ; Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92037, USA.
  • Lu LF; Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92037, USA.
  • Esteban CR; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Izpisua Belmonte JC; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address: belmonte@salk.edu.
Cell ; 171(7): 1495-1507.e15, 2017 Dec 14.
Article in En | MEDLINE | ID: mdl-29224783
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Therapy / Gene Targeting / Muscular Dystrophy, Duchenne / Epigenesis, Genetic / Utrophin / CRISPR-Cas Systems Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cell Year: 2017 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Therapy / Gene Targeting / Muscular Dystrophy, Duchenne / Epigenesis, Genetic / Utrophin / CRISPR-Cas Systems Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cell Year: 2017 Type: Article Affiliation country: United States