EARLY gestational exposure to isoflurane causes persistent cell loss in the dentate gyrus of adult male rats.

Palanisamy, Arvind; Crosby, Gregory; Culley, Deborah J

Palanisamy, Arvind; Crosby, Gregory; Culley, Deborah J.

Affiliation

Palanisamy A; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. arvind.palanisamy@wustl.edu.
Crosby G; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA. arvind.palanisamy@wustl.edu.
Culley DJ; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Behav Brain Funct ; 13(1): 14, 2017 Dec 26.

Article in En | MEDLINE | ID: mdl-29279051

Subject(s)

Hippocampus/drug effects; Isoflurane/adverse effects; Spatial Memory/drug effects; Animals; Dentate Gyrus/pathology; Female; Hippocampus/pathology; Isoflurane/pharmacology; Male; Neurons/pathology; Pregnancy; Pregnancy Trimester, Second/drug effects; Prenatal Exposure Delayed Effects; Pyramidal Cells/pathology; Rats; Rats, Sprague-Dawley

Key words

Anesthesia during pregnancy; Anesthetic neurotoxicity; CA1 region; Dentate gyrus; Hippocampus; Maternal anesthesia; Spatial working memory; Stereology

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spatial Memory / Hippocampus / Isoflurane Type of study: Etiology_studies Limits: Animals / Pregnancy Language: En Journal: Behav Brain Funct Journal subject: CEREBRO / CIENCIAS DO COMPORTAMENTO Year: 2017 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google