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Repeat doses of antibody to serum amyloid P component clear amyloid deposits in patients with systemic amyloidosis.
Richards, Duncan B; Cookson, Louise M; Barton, Sharon V; Liefaard, Lia; Lane, Thirusha; Hutt, David F; Ritter, James M; Fontana, Marianna; Moon, James C; Gillmore, Julian D; Wechalekar, Ashutosh; Hawkins, Philip N; Pepys, Mark B.
Affiliation
  • Richards DB; GlaxoSmithKline Research and Development, Stevenage, Herts SG1 2NY, UK.
  • Cookson LM; GlaxoSmithKline Research and Development, Stevenage, Herts SG1 2NY, UK.
  • Barton SV; GlaxoSmithKline Research and Development, Stevenage, Herts SG1 2NY, UK.
  • Liefaard L; GlaxoSmithKline Research and Development, Stevenage, Herts SG1 2NY, UK.
  • Lane T; National Health Service National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, University College London and Royal Free Hospital, London NW3 2PF, UK.
  • Hutt DF; National Health Service National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, University College London and Royal Free Hospital, London NW3 2PF, UK.
  • Ritter JM; Quintiles Drug Research Unit, Guy's Hospital, London SE1 1YR, UK.
  • Fontana M; National Health Service National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, University College London and Royal Free Hospital, London NW3 2PF, UK.
  • Moon JC; University College London Institute of Cardiovascular Science and Barts Heart Centre, St Bartholomew's Hospital, London EC1A 7BE, UK.
  • Gillmore JD; National Health Service National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, University College London and Royal Free Hospital, London NW3 2PF, UK.
  • Wechalekar A; National Health Service National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, University College London and Royal Free Hospital, London NW3 2PF, UK.
  • Hawkins PN; National Health Service National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, University College London and Royal Free Hospital, London NW3 2PF, UK.
  • Pepys MB; National Health Service National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, University College London and Royal Free Hospital, London NW3 2PF, UK. m.pepys@ucl.ac.uk.
Sci Transl Med ; 10(422)2018 01 03.
Article in En | MEDLINE | ID: mdl-29298867

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serum Amyloid P-Component / Amyloidosis / Antibodies Limits: Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2018 Type: Article Affiliation country: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serum Amyloid P-Component / Amyloidosis / Antibodies Limits: Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2018 Type: Article Affiliation country: United kingdom