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Positively selected enhancer elements endow osteosarcoma cells with metastatic competence.
Morrow, James J; Bayles, Ian; Funnell, Alister P W; Miller, Tyler E; Saiakhova, Alina; Lizardo, Michael M; Bartels, Cynthia F; Kapteijn, Maaike Y; Hung, Stevephen; Mendoza, Arnulfo; Dhillon, Gursimran; Chee, Daniel R; Myers, Jay T; Allen, Frederick; Gambarotti, Marco; Righi, Alberto; DiFeo, Analisa; Rubin, Brian P; Huang, Alex Y; Meltzer, Paul S; Helman, Lee J; Picci, Piero; Versteeg, Henri H; Stamatoyannopoulos, John A; Khanna, Chand; Scacheri, Peter C.
Affiliation
  • Morrow JJ; Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA.
  • Bayles I; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio, USA.
  • Funnell APW; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio, USA.
  • Miller TE; Altius Institute for Biomedical Sciences, Seattle, Washington, USA.
  • Saiakhova A; Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA.
  • Lizardo MM; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio, USA.
  • Bartels CF; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Kapteijn MY; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio, USA.
  • Hung S; Thrombosis and Hemostasis Division, Department of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands.
  • Mendoza A; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio, USA.
  • Dhillon G; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Chee DR; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio, USA.
  • Myers JT; Department of Genome Sciences, University of Washington, Seattle, Washington, USA.
  • Allen F; Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA.
  • Gambarotti M; Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA.
  • Righi A; Laboratory of Experimental Oncology, Istituto Ortopedico Rizzoli, Bologna, Italy.
  • DiFeo A; Laboratory of Experimental Oncology, Istituto Ortopedico Rizzoli, Bologna, Italy.
  • Rubin BP; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, USA.
  • Huang AY; Departments of Anatomic Pathology and Molecular Genetics, Cleveland Clinic, Lerner Research Institute and Taussig Cancer Center, Cleveland, Ohio, USA.
  • Meltzer PS; Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA.
  • Helman LJ; Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA.
  • Picci P; Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Versteeg HH; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Stamatoyannopoulos JA; Laboratory of Experimental Oncology, Istituto Ortopedico Rizzoli, Bologna, Italy.
  • Khanna C; Thrombosis and Hemostasis Division, Department of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands.
  • Scacheri PC; Altius Institute for Biomedical Sciences, Seattle, Washington, USA.
Nat Med ; 24(2): 176-185, 2018 02.
Article in En | MEDLINE | ID: mdl-29334376

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteosarcoma / Enhancer Elements, Genetic / Carcinogenesis / Lung Neoplasms Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2018 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteosarcoma / Enhancer Elements, Genetic / Carcinogenesis / Lung Neoplasms Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2018 Type: Article Affiliation country: United States