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Increased Epitope Complexity Correlated with Antibody Affinity Maturation and a Novel Binding Mode Revealed by Structures of Rabbit Antibodies against the Third Variable Loop (V3) of HIV-1 gp120.
Pan, Ruimin; Qin, Yali; Banasik, Marisa; Lees, William; Shepherd, Adrian J; Cho, Michael W; Kong, Xiang-Peng.
Affiliation
  • Pan R; Department of Biochemistry and Molecular Pharmacology, NYU School of Medicine, New York, New York, USA.
  • Qin Y; Department of Biomedical Sciences, Iowa State University, Ames, Iowa, USA.
  • Banasik M; Department of Biomedical Sciences, Iowa State University, Ames, Iowa, USA.
  • Lees W; Institute of Structural and Molecular Biology, Birkbeck College, University of London, London, United Kingdom.
  • Shepherd AJ; Institute of Structural and Molecular Biology, Birkbeck College, University of London, London, United Kingdom.
  • Cho MW; Department of Biomedical Sciences, Iowa State University, Ames, Iowa, USA mcho@iastate.edu xiangpeng.kong@med.nyu.edu.
  • Kong XP; Department of Biochemistry and Molecular Pharmacology, NYU School of Medicine, New York, New York, USA mcho@iastate.edu xiangpeng.kong@med.nyu.edu.
J Virol ; 92(7)2018 04 01.
Article in En | MEDLINE | ID: mdl-29343576
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Antibodies / HIV Envelope Protein gp120 / HIV Infections / HIV-1 / Antibodies, Monoclonal / Epitopes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Virol Year: 2018 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Antibodies / HIV Envelope Protein gp120 / HIV Infections / HIV-1 / Antibodies, Monoclonal / Epitopes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Virol Year: 2018 Type: Article Affiliation country: United States