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Asparagine bioavailability governs metastasis in a model of breast cancer.
Knott, Simon R V; Wagenblast, Elvin; Khan, Showkhin; Kim, Sun Y; Soto, Mar; Wagner, Michel; Turgeon, Marc-Olivier; Fish, Lisa; Erard, Nicolas; Gable, Annika L; Maceli, Ashley R; Dickopf, Steffen; Papachristou, Evangelia K; D'Santos, Clive S; Carey, Lisa A; Wilkinson, John E; Harrell, J Chuck; Perou, Charles M; Goodarzi, Hani; Poulogiannis, George; Hannon, Gregory J.
Affiliation
  • Knott SRV; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.
  • Wagenblast E; Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.
  • Khan S; Center for Bioinformatics and Functional Genomics, Department of Biomedical Sciences, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, California 90048, USA.
  • Kim SY; Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.
  • Soto M; Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
  • Wagner M; Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
  • Turgeon MO; Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.
  • Fish L; New York Genome Center, 101 6th Avenue, New York, New York 10013, USA.
  • Erard N; Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.
  • Gable AL; Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.
  • Maceli AR; Division of Cancer Biology, The Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.
  • Dickopf S; Division of Cancer Biology, The Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.
  • Papachristou EK; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California 94158, USA.
  • D'Santos CS; Department of Urology, University of California, San Francisco, San Francisco, California 94158, USA.
  • Carey LA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California 94158, USA.
  • Wilkinson JE; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.
  • Harrell JC; Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.
  • Perou CM; Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.
  • Goodarzi H; Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.
  • Poulogiannis G; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.
  • Hannon GJ; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.
Nature ; 554(7692): 378-381, 2018 02 15.
Article in En | MEDLINE | ID: mdl-29414946

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asparagine / Breast Neoplasms / Neoplasm Metastasis Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nature Year: 2018 Type: Article Affiliation country: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asparagine / Breast Neoplasms / Neoplasm Metastasis Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nature Year: 2018 Type: Article Affiliation country: United kingdom