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Neurofilament light chain and tau concentrations are markedly increased in the serum of patients with sporadic Creutzfeldt-Jakob disease, and tau correlates with rate of disease progression.
Thompson, Andrew Geoffrey Bourne; Luk, Connie; Heslegrave, Amanda J; Zetterberg, Henrik; Mead, Simon H; Collinge, John; Jackson, Graham S.
Affiliation
  • Thompson AGB; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, UK.
  • Luk C; NHS National Prion Clinic, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK.
  • Heslegrave AJ; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, UK.
  • Zetterberg H; Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.
  • Mead SH; UK Dementia Research Institute at UCL, London, UK.
  • Collinge J; Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.
  • Jackson GS; UK Dementia Research Institute at UCL, London, UK.
J Neurol Neurosurg Psychiatry ; 89(9): 955-961, 2018 09.
Article in En | MEDLINE | ID: mdl-29487167
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Creutzfeldt-Jakob Syndrome / Neurofilament Proteins / Tau Proteins Type of study: Diagnostic_studies / Observational_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: J Neurol Neurosurg Psychiatry Year: 2018 Type: Article Affiliation country: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Creutzfeldt-Jakob Syndrome / Neurofilament Proteins / Tau Proteins Type of study: Diagnostic_studies / Observational_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: J Neurol Neurosurg Psychiatry Year: 2018 Type: Article Affiliation country: United kingdom