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Combination of common and novel rare NUDT15 variants improves predictive sensitivity of thiopurine-induced leukopenia in children with acute lymphoblastic leukemia.
Zhu, Yiping; Yin, Dandan; Su, Yali; Xia, Xuyang; Moriyama, Takaya; Nishii, Rina; Liao, Fei; Zhang, Shouyue; Guo, Xia; Hou, Qianqian; Ai, Yuan; Zhou, Xueyan; Sun, Shuwen; Zhang, Duyu; Zhang, Yan; Lin, Chao; Deng, Yiqi; Lu, Xiaoxi; Wang, Yuelan; Ma, Zhigui; Wang, Heyao; Liu, Bo; Yang, Li; Zhang, Wei; Yang, Jun J; Shu, Yang; Gao, Ju; Xu, Heng.
Affiliation
  • Zhu Y; Department of Pediatric Hematology/Oncology, West China Second Hospital, Sichuan University, Chengdu, China.
  • Yin D; Department of Laboratory Medicine, Precision Medicine Center, State Key Laboratory of Biotherapy and Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
  • Su Y; Department of Pediatric Hematology/Oncology, West China Second Hospital, Sichuan University, Chengdu, China.
  • Xia X; Department of Laboratory Medicine, Precision Medicine Center, State Key Laboratory of Biotherapy and Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
  • Moriyama T; Department of Pharmaceutical Sciences and Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Nishii R; Department of Pharmaceutical Sciences and Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Liao F; Department of Laboratory Medicine, Precision Medicine Center, State Key Laboratory of Biotherapy and Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
  • Zhang S; Department of Laboratory Medicine, Precision Medicine Center, State Key Laboratory of Biotherapy and Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
  • Guo X; Department of Pediatric Hematology/Oncology, West China Second Hospital, Sichuan University, Chengdu, China.
  • Hou Q; Department of Laboratory Medicine, Precision Medicine Center, State Key Laboratory of Biotherapy and Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
  • Ai Y; Department of Pediatric Hematology/Oncology, West China Second Hospital, Sichuan University, Chengdu, China.
  • Zhou X; Department of Laboratory Medicine, Precision Medicine Center, State Key Laboratory of Biotherapy and Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
  • Sun S; Department of Pediatric Hematology/Oncology, West China Second Hospital, Sichuan University, Chengdu, China.
  • Zhang D; Department of Laboratory Medicine, Precision Medicine Center, State Key Laboratory of Biotherapy and Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
  • Zhang Y; Department of Thoracic Oncology, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
  • Lin C; Department of Pediatric Hematology/Oncology, West China Second Hospital, Sichuan University, Chengdu, China.
  • Deng Y; Department of Laboratory Medicine, Precision Medicine Center, State Key Laboratory of Biotherapy and Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
  • Lu X; Department of Pediatric Hematology/Oncology, West China Second Hospital, Sichuan University, Chengdu, China.
  • Wang Y; Department of Laboratory Medicine, Precision Medicine Center, State Key Laboratory of Biotherapy and Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
  • Ma Z; Department of Pediatric Hematology/Oncology, West China Second Hospital, Sichuan University, Chengdu, China.
  • Wang H; Department of Precision Medicine, China-Japan Friendship Hospital, Beijing, China.
  • Liu B; State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
  • Yang L; State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
  • Zhang W; Department of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Xiangya Hospital, Central South University, Changsha, China.
  • Yang JJ; Department of Pharmaceutical Sciences and Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Shu Y; Department of Laboratory Medicine, Precision Medicine Center, State Key Laboratory of Biotherapy and Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China xuheng81916@scu.edu.cn gaoju651220@126.com shuyang19
  • Gao J; Department of Pediatric Hematology/Oncology, West China Second Hospital, Sichuan University, Chengdu, China xuheng81916@scu.edu.cn gaoju651220@126.com shuyang1986@gmail.com.
  • Xu H; Department of Laboratory Medicine, Precision Medicine Center, State Key Laboratory of Biotherapy and Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China xuheng81916@scu.edu.cn gaoju651220@126.com shuyang19
Haematologica ; 103(7): e293-e295, 2018 07.
Article in En | MEDLINE | ID: mdl-29519865
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrophosphatases / Genetic Variation / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Pharmacogenomic Variants / Leukopenia / Mercaptopurine Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Child / Humans Language: En Journal: Haematologica Year: 2018 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrophosphatases / Genetic Variation / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Pharmacogenomic Variants / Leukopenia / Mercaptopurine Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Child / Humans Language: En Journal: Haematologica Year: 2018 Type: Article Affiliation country: China