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Myeloid-specific Acat1 ablation attenuates inflammatory responses in macrophages, improves insulin sensitivity, and suppresses diet-induced obesity.
Huang, Li-Hao; Melton, Elaina M; Li, Haibo; Sohn, Paul; Jung, DaeYoung; Tsai, Ching-Yi; Ma, Tian; Sano, Hiroyuki; Ha, HyeKyung; Friedline, Randall H; Kim, Jason K; Usherwood, Edward; Chang, Catherine C Y; Chang, Ta-Yuan.
Affiliation
  • Huang LH; Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth , Hanover, New Hampshire.
  • Melton EM; Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth , Hanover, New Hampshire.
  • Li H; Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth , Hanover, New Hampshire.
  • Sohn P; Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth , Hanover, New Hampshire.
  • Jung D; Program in Molecular Medicine, University of Massachusetts Medical School , Worcester, Massachusetts.
  • Tsai CY; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire.
  • Ma T; Department of Pharmacology and Toxicology, Geisel School of Medicine at Dartmouth , Hanover, New Hampshire.
  • Sano H; Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth , Hanover, New Hampshire.
  • Ha H; Program in Molecular Medicine, University of Massachusetts Medical School , Worcester, Massachusetts.
  • Friedline RH; Program in Molecular Medicine, University of Massachusetts Medical School , Worcester, Massachusetts.
  • Kim JK; Program in Molecular Medicine, University of Massachusetts Medical School , Worcester, Massachusetts.
  • Usherwood E; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire.
  • Chang CCY; Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth , Hanover, New Hampshire.
  • Chang TY; Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth , Hanover, New Hampshire.
Am J Physiol Endocrinol Metab ; 315(3): E340-E356, 2018 09 01.
Article in En | MEDLINE | ID: mdl-29533741
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acetyl-CoA C-Acetyltransferase / Insulin Resistance / Sterol O-Acyltransferase / Diet / Inflammation / Macrophages / Obesity Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Am J Physiol Endocrinol Metab Journal subject: ENDOCRINOLOGIA / FISIOLOGIA / METABOLISMO Year: 2018 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acetyl-CoA C-Acetyltransferase / Insulin Resistance / Sterol O-Acyltransferase / Diet / Inflammation / Macrophages / Obesity Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Am J Physiol Endocrinol Metab Journal subject: ENDOCRINOLOGIA / FISIOLOGIA / METABOLISMO Year: 2018 Type: Article