2,3,5,4'-Tetrahydroxystilbene-2-O-ß-glucoside potentiates self-renewal of human dental pulp stem cells via the AMPK/ERK/SIRT1 axis.

Lin, C-Y; Chin, Y-T; Kuo, P-J; Lee, H-W; Huang, H-M; Lin, H-Y; Weng, I-T; Hsiung, C-N; Chan, Y-H; Lee, S-Y

Lin, C-Y; Chin, Y-T; Kuo, P-J; Lee, H-W; Huang, H-M; Lin, H-Y; Weng, I-T; Hsiung, C-N; Chan, Y-H; Lee, S-Y.

Affiliation

Lin CY; School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Chin YT; Research Center of Tooth Bank and Dental Stem Cell Technology, Taipei Medical University, Taipei, Taiwan.
Kuo PJ; Taipei Cancer Center, Taipei Medical University, Taipei, Taiwan.
Lee HW; PhD Program for Cancer Biology and Drug Discovery College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Huang HM; Department of Periodontology School of Dentistry, National Defense Medical Center and Tri-Service General Hospital, Taipei, Taiwan.
Lin HY; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan.
Weng IT; Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Hsiung CN; School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Chan YH; Taipei Cancer Center, Taipei Medical University, Taipei, Taiwan.
Lee SY; PhD Program for Cancer Biology and Drug Discovery College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.

Int Endod J ; 51(10): 1159-1170, 2018 Oct.

Article in En | MEDLINE | ID: mdl-29635697

Subject(s)

Dental Pulp/cytology; Glucosides/pharmacology; Stem Cells/drug effects; Stilbenes/pharmacology; Blotting, Western; Cell Proliferation/drug effects; Cell Survival/drug effects; Dental Pulp/drug effects; Extracellular Signal-Regulated MAP Kinases/metabolism; Gene Expression; Humans; MAP Kinase Signaling System/physiology; RNA, Messenger/metabolism; Real-Time Polymerase Chain Reaction; Sirtuin 1/metabolism; Stem Cells/physiology

Key words

2,3,5,4'-tetrahydroxystilbene-2-O-ß-glucoside; dental pulp stem cells; pluripotency; proliferation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Stilbenes / Dental Pulp / Glucosides Limits: Humans Language: En Journal: Int Endod J Year: 2018 Type: Article Affiliation country: Taiwan

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