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Evaluation of avoralstat, an oral kallikrein inhibitor, in a Phase 3 hereditary angioedema prophylaxis trial: The OPuS-2 study.
Riedl, M A; Aygören-Pürsün, E; Baker, J; Farkas, H; Anderson, J; Bernstein, J A; Bouillet, L; Busse, P; Manning, M; Magerl, M; Gompels, M; Huissoon, A P; Longhurst, H; Lumry, W; Ritchie, B; Shapiro, R; Soteres, D; Banerji, A; Cancian, M; Johnston, D T; Craig, T J; Launay, D; Li, H H; Liebhaber, M; Nickel, T; Offenberger, J; Rae, W; Schrijvers, R; Triggiani, M; Wedner, H J; Dobo, S; Cornpropst, M; Clemons, D; Fang, L; Collis, P; Sheridan, W P; Maurer, M.
Affiliation
  • Riedl MA; Division of Rheumatology, Allergy & Immunology, University of California San Diego, San Diego, CA, USA.
  • Aygören-Pürsün E; Department for Children and Adolescents, University Hospital Frankfurt, Frankfurt, Germany.
  • Baker J; Baker Allergy Asthma Dermatology Research Center, Portland, OR, USA.
  • Farkas H; 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.
  • Anderson J; Clinical Research Center of Alabama, Birmingham, AL, USA.
  • Bernstein JA; Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.
  • Bouillet L; Internal Medicine, National Reference Centre of Angioedema, Grenoble University Hospital, Grenoble, France.
  • Busse P; Division of Clinical Immunology and Allergy, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Manning M; Medical Research of Arizona, Allergy, Asthma & Immunology Associates, Scottsdale, AZ, USA.
  • Magerl M; Dermatology, Venerology and Allergology, Charite - Universitätsmedizin Berlin, Berlin, Germany.
  • Gompels M; Immunology, North Bristol NHS Trust, Bristol, UK.
  • Huissoon AP; Department of Allergy and Immunology, Heartlands Hospital, Birmingham, UK.
  • Longhurst H; Immunology, Addenbrookes Hospital, Cambridge University Hospitals, Cambridge, UK.
  • Lumry W; Allergy and Asthma Research Associates Research Center, Dallas, TX, USA.
  • Ritchie B; Division of Hematology, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
  • Shapiro R; Immunology, Midwest Immunology Clinic, Plymouth, MN, USA.
  • Soteres D; Asthma and Allergy Associates PC, Colorado Springs, CO, USA.
  • Banerji A; Division of Rheumatology, Allergy& Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Cancian M; Department of Medicine, University of Padova, Padova, Italy.
  • Johnston DT; Asthma & Allergy Specialists, P.A., Charlotte, NC, USA.
  • Craig TJ; Department of Medicine and Pediatrics, Penn State Hershey Allergy Asthma, and Immunology, Hershey, PA, USA.
  • Launay D; Internal Medicine, CHRU Lille, France, France.
  • Li HH; Institute for Asthma and Allergy, Chevy Chase, MD, USA.
  • Liebhaber M; Allergy and Immunology, Sansum Clinic, Santa Barbara, CA, USA.
  • Nickel T; Allergy & Immunology, Allergy Clinic of Tulsa, Tulsa, OK, USA.
  • Offenberger J; Allergy and Asthma Relief Experts, Grenada Hills, CA, USA.
  • Rae W; Allergy & Clinical Immunology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
  • Schrijvers R; Laboratory of Clinical Immunology, KU Leuven, Leuven, Belgium.
  • Triggiani M; Division of Allergy and Clinical Immunology, University of Salerno, Salerno, Italy.
  • Wedner HJ; Division of Allergy and Immunology, Washington University School of Medicine, St. Louis, MO, USA.
  • Dobo S; Biocryst Pharmaceuticals, Durham, NC, USA.
  • Cornpropst M; Biocryst Pharmaceuticals, Durham, NC, USA.
  • Clemons D; Biocryst Pharmaceuticals, Durham, NC, USA.
  • Fang L; Statistics, PharStat, Inc., Raleigh, NC, USA.
  • Collis P; Biocryst Pharmaceuticals, Durham, NC, USA.
  • Sheridan WP; Biocryst Pharmaceuticals, Durham, NC, USA.
  • Maurer M; Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Allergy ; 73(9): 1871-1880, 2018 Sep.
Article in En | MEDLINE | ID: mdl-29688579
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasma Kallikrein / Enzyme Inhibitors / Angioedemas, Hereditary Type of study: Clinical_trials / Diagnostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Allergy Year: 2018 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasma Kallikrein / Enzyme Inhibitors / Angioedemas, Hereditary Type of study: Clinical_trials / Diagnostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Allergy Year: 2018 Type: Article Affiliation country: United States