Chinese Herbal Medicine Xueshuantong Enhances Cerebral Blood Flow and Improves Neural Functions in Alzheimer's Disease Mice.

Huang, Yangmei; Guo, Baihong; Shi, Bihua; Gao, Qingtao; Zhou, Qiang

Huang, Yangmei; Guo, Baihong; Shi, Bihua; Gao, Qingtao; Zhou, Qiang.

Affiliation

Huang Y; School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
Guo B; School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
Shi B; School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
Gao Q; School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
Zhou Q; School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.

J Alzheimers Dis ; 63(3): 1089-1107, 2018.

Article in En | MEDLINE | ID: mdl-29710701

Subject(s)

Alzheimer Disease/drug therapy; Antipsychotic Agents/therapeutic use; Brain/drug effects; Cerebrovascular Circulation/drug effects; Drugs, Chinese Herbal/therapeutic use; Alzheimer Disease/genetics; Alzheimer Disease/pathology; Alzheimer Disease/physiopathology; Amyloid beta-Peptides/metabolism; Amyloid beta-Protein Precursor/genetics; Animals; Brain/metabolism; Brain/pathology; Brain/ultrastructure; Cerebrovascular Circulation/genetics; Disease Models, Animal; Female; Humans; Maze Learning/drug effects; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation/genetics; Presenilin-1/genetics; Reaction Time/drug effects; Reaction Time/genetics; Rotarod Performance Test; Synapses/drug effects; Synapses/metabolism; Synaptophysin/metabolism; Time Factors

Key words

Alzheimer's disease; Aß plaque; Chinese herbal medicine; cerebral blood flow; synapse; two-photon imaging

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antipsychotic Agents / Brain / Drugs, Chinese Herbal / Cerebrovascular Circulation / Alzheimer Disease Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: J Alzheimers Dis Journal subject: GERIATRIA / NEUROLOGIA Year: 2018 Type: Article Affiliation country: China

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