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Arginase upregulation and eNOS uncoupling contribute to impaired endothelium-dependent vasodilation in a rat model of intrauterine growth restriction.
Grandvuillemin, Isabelle; Buffat, Christophe; Boubred, Farid; Lamy, Edouard; Fromonot, Julien; Charpiot, Philippe; Simoncini, Stephanie; Sabatier, Florence; Dignat-George, Françoise; Peyter, Anne-Christine; Simeoni, Umberto; Yzydorczyk, Catherine.
Affiliation
  • Grandvuillemin I; Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Recherche Agronomique (INRA), Centre de Recherche en Cardiovasculaire et Nutrition (C2VN), Aix Marseille University, Marseille, France.
  • Buffat C; Department of Neonatology, Assistance Publique Hôpitaux de Marseille (APHM), Centre Hospitalier Universitaire (CHU) La Conception, Marseille, France.
  • Boubred F; Unité de Recherche sur les Maladies Infectieuses Tropicales, Emergentes, Laboratory of Biochimical and Molecular Biology, Centre National de la Recherche Scientifique (CNRS), APHM, CHU la Conception, Aix Marseille University, Marseille, France.
  • Lamy E; Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Recherche Agronomique (INRA), Centre de Recherche en Cardiovasculaire et Nutrition (C2VN), Aix Marseille University, Marseille, France.
  • Fromonot J; Department of Neonatology, Assistance Publique Hôpitaux de Marseille (APHM), Centre Hospitalier Universitaire (CHU) La Conception, Marseille, France.
  • Charpiot P; CNRS, Inst Movement Sci (ISM); Service Central de la Qualité et de l'Information Pharmaceutiques, APHM, Aix-Marseille University, Marseille, France.
  • Simoncini S; UMR MD2 and Institute of Biological Research French Defense Ministry (IRBA), Aix-Marseille University, Marseille, France.
  • Sabatier F; CNRS, Inst Movement Sci (ISM); Service Central de la Qualité et de l'Information Pharmaceutiques, APHM, Aix-Marseille University, Marseille, France.
  • Dignat-George F; Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Recherche Agronomique (INRA), Centre de Recherche en Cardiovasculaire et Nutrition (C2VN), Aix Marseille University, Marseille, France.
  • Peyter AC; Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Recherche Agronomique (INRA), Centre de Recherche en Cardiovasculaire et Nutrition (C2VN), Aix Marseille University, Marseille, France.
  • Simeoni U; Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Recherche Agronomique (INRA), Centre de Recherche en Cardiovasculaire et Nutrition (C2VN), Aix Marseille University, Marseille, France.
  • Yzydorczyk C; Neonatal Research Laboratory, Clinic of Neonatology, Department Woman-Mother-Child, Centre Hospitalier Universitaire Vaudois (CHUV), University of Lausanne, Lausanne, Switzerland.
Am J Physiol Regul Integr Comp Physiol ; 315(3): R509-R520, 2018 09 01.
Article in En | MEDLINE | ID: mdl-29741931
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aorta, Thoracic / Arginase / Vasodilation / Endothelium, Vascular / Nitric Oxide Synthase Type III / Fetal Growth Retardation Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Pregnancy Language: En Journal: Am J Physiol Regul Integr Comp Physiol Journal subject: FISIOLOGIA Year: 2018 Type: Article Affiliation country: France
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aorta, Thoracic / Arginase / Vasodilation / Endothelium, Vascular / Nitric Oxide Synthase Type III / Fetal Growth Retardation Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Pregnancy Language: En Journal: Am J Physiol Regul Integr Comp Physiol Journal subject: FISIOLOGIA Year: 2018 Type: Article Affiliation country: France