Soya protein ß-conglycinin ameliorates fatty liver and obesity in diet-induced obese mice through the down-regulation of PPARÎ³.

Li, Dongyang; Ikaga, Reina; Yamazaki, Tomomi

Li, Dongyang; Ikaga, Reina; Yamazaki, Tomomi.

Affiliation

Li D; 1Department of Nutritional Science,National Institute of Health and Nutrition,National Institutes of Biomedical Innovation, Health and Nutrition,1-23-1 Toyama,Shinjuku-ku,Tokyo 162-8636,Japan.
Ikaga R; 1Department of Nutritional Science,National Institute of Health and Nutrition,National Institutes of Biomedical Innovation, Health and Nutrition,1-23-1 Toyama,Shinjuku-ku,Tokyo 162-8636,Japan.
Yamazaki T; 1Department of Nutritional Science,National Institute of Health and Nutrition,National Institutes of Biomedical Innovation, Health and Nutrition,1-23-1 Toyama,Shinjuku-ku,Tokyo 162-8636,Japan.

Br J Nutr ; 119(11): 1220-1232, 2018 06.

Article in En | MEDLINE | ID: mdl-29770757

Subject(s)

Antigens, Plant/pharmacology; Down-Regulation/drug effects; Fatty Liver/prevention & control; Globulins/pharmacology; Obesity/prevention & control; PPAR gamma/metabolism; Seed Storage Proteins/pharmacology; Soybean Proteins/pharmacology; Adipose Tissue/drug effects; Adipose Tissue/metabolism; Animal Feed/analysis; Animals; Antigens, Plant/administration & dosage; Carbon Dioxide; Diet; Epididymis; Gene Expression Regulation/drug effects; Globulins/administration & dosage; Male; Mice; Obesity/etiology; Oxygen Consumption; PPAR gamma/genetics; Seed Storage Proteins/administration & dosage; Soybean Proteins/administration & dosage

Key words

BW body weight; DIO diet-induced obese; HF high fat; LF low fat; MF medium fat; NAFLD non-alcoholic fatty liver disease; SREBP-1c sterol regulatory element-binding protein-1c; TC total cholesterol; VCO2 carbon dioxide production; WAT white adipose tissue; Inflammation; Non-alcoholic fatty liver disease; Obesity; PPARÎ³; ß-Conglycinin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Down-Regulation / Soybean Proteins / PPAR gamma / Antigens, Plant / Seed Storage Proteins / Fatty Liver / Globulins / Obesity Type of study: Etiology_studies Limits: Animals Language: En Journal: Br J Nutr Year: 2018 Type: Article Affiliation country: Japan

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