Polymorphic sites preferentially avoid co-evolving residues in MHC class I proteins.

Dib, Linda; Salamin, Nicolas; Gfeller, David

Dib, Linda; Salamin, Nicolas; Gfeller, David.

Affiliation

Dib L; Department of Oncology, Ludwig Institute for Cancer Research, University of Lausanne, Switzerland.
Salamin N; Swiss Institutes of Bioinformatics, Quartier Sorge, Lausanne, Switzerland.
Gfeller D; Swiss Institutes of Bioinformatics, Quartier Sorge, Lausanne, Switzerland.

PLoS Comput Biol ; 14(5): e1006188, 2018 05.

Article in En | MEDLINE | ID: mdl-29782520

Subject(s)

Binding Sites/genetics; Evolution, Molecular; Histocompatibility Antigens Class I; Polymorphism, Genetic/genetics; Animals; Histocompatibility Antigens Class I/chemistry; Histocompatibility Antigens Class I/genetics; Histocompatibility Antigens Class I/metabolism; Humans; Models, Molecular; Phylogeny; Protein Stability; Vertebrates/genetics

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / Binding Sites / Histocompatibility Antigens Class I / Evolution, Molecular Limits: Animals / Humans Language: En Journal: PLoS Comput Biol Journal subject: BIOLOGIA / INFORMATICA MEDICA Year: 2018 Type: Article Affiliation country: Switzerland

Fulltext

XML

PubMed Links

Search on Google