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Bi-directional regulation of cartilage metabolism by inhibiting BET proteins-analysis of the effect of I-BET151 on human chondrocytes and murine joints.
Dai, Jin; Zhou, Sheng; Ge, Qiting; Qin, Jinzhong; Chen, Dongyang; Xu, Zhihong; Shi, Dongquan; Li, Jianxin; Ju, Huangxian; Cao, Yi; Zheng, Minghao; Li, Chao Jun; Gao, Xiang; Teng, Huajian; Jiang, Qing.
Affiliation
  • Dai J; Department of Sports Medicine and Adult Reconstructive Surgery, Drum Tower Hospital, School of Medicine, Nanjing University, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, People's Republic of China.
  • Zhou S; Department of Sports Medicine and Adult Reconstructive Surgery, Drum Tower Hospital, School of Medicine, Nanjing University, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, People's Republic of China.
  • Ge Q; Model Animal Research Center of Nanjing University, Xuefu Road, Nanjing, 210032, Jiangsu, People's Republic of China.
  • Qin J; Model Animal Research Center of Nanjing University, Xuefu Road, Nanjing, 210032, Jiangsu, People's Republic of China.
  • Chen D; Department of Sports Medicine and Adult Reconstructive Surgery, Drum Tower Hospital, School of Medicine, Nanjing University, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, People's Republic of China.
  • Xu Z; Department of Sports Medicine and Adult Reconstructive Surgery, Drum Tower Hospital, School of Medicine, Nanjing University, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, People's Republic of China.
  • Shi D; Department of Sports Medicine and Adult Reconstructive Surgery, Drum Tower Hospital, School of Medicine, Nanjing University, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, People's Republic of China.
  • Li J; State Key Laboratory of Analytical Chemistry for Life Science, Nanjing University, Hankou Road, Nanjing, 210093, People's Republic of China.
  • Ju H; State Key Laboratory of Analytical Chemistry for Life Science, Nanjing University, Hankou Road, Nanjing, 210093, People's Republic of China.
  • Cao Y; Collaborative Innovation Center of Advanced Microstructures, National Laboratory of Solid State Microstructure and Department of Physics, Nanjing University, Hankou Road, Nanjing, 210093, People's Republic of China.
  • Zheng M; Sir Charles Gairdner Hospital, School of Surgery, The University of Western Australia, 35 Stirling Highway, Perth, 6009, Australia.
  • Li CJ; State Key Laboratory of Pharmaceutical Biotechnology and Jiangsu Key Laboratory of Molecular Medicine, Model Animal Research Center and School of Medicine, Nanjing University, Nanjing, 210093, People's Republic of China.
  • Gao X; Model Animal Research Center of Nanjing University, Xuefu Road, Nanjing, 210032, Jiangsu, People's Republic of China.
  • Teng H; Department of Sports Medicine and Adult Reconstructive Surgery, Drum Tower Hospital, School of Medicine, Nanjing University, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, People's Republic of China. tenghj@hotmail.com.
  • Jiang Q; Model Animal Research Center of Nanjing University, Xuefu Road, Nanjing, 210032, Jiangsu, People's Republic of China. tenghj@hotmail.com.
J Orthop Surg Res ; 13(1): 118, 2018 May 21.
Article in En | MEDLINE | ID: mdl-29784003
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cartilage, Articular / Chondrocytes / Heterocyclic Compounds, 4 or More Rings / Knee Joint Type of study: Prognostic_studies Limits: Aged / Animals / Humans / Male / Middle aged Language: En Journal: J Orthop Surg Res Year: 2018 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cartilage, Articular / Chondrocytes / Heterocyclic Compounds, 4 or More Rings / Knee Joint Type of study: Prognostic_studies Limits: Aged / Animals / Humans / Male / Middle aged Language: En Journal: J Orthop Surg Res Year: 2018 Type: Article