Proline hydroxylation at different sites in hypoxia-inducible factor 1&#945; modulates its interactions with the von Hippel-Lindau tumor suppressor protein.

Qian, Hongsheng; Zou, Yu; Tang, Yiming; Gong, Yehong; Qian, Zhenyu; Wei, Guanghong; Zhang, Qingwen

Proline hydroxylation at different sites in hypoxia-inducible factor 1α modulates its interactions with the von Hippel-Lindau tumor suppressor protein.

Qian, Hongsheng; Zou, Yu; Tang, Yiming; Gong, Yehong; Qian, Zhenyu; Wei, Guanghong; Zhang, Qingwen.

Affiliation

Qian H; College of Physical Education and Training, Shanghai University of Sport, 399 Changhai Road, Shanghai 200438, China. zqw@sus.edu.cn.

Phys Chem Chem Phys ; 20(27): 18756-18765, 2018 Jul 11.

Article in En | MEDLINE | ID: mdl-29961792

Subject(s)

Hypoxia-Inducible Factor 1, alpha Subunit/chemistry; Proline/chemistry; Von Hippel-Lindau Tumor Suppressor Protein/chemistry; Binding Sites; Hydroxylation; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; Thermodynamics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proline / Von Hippel-Lindau Tumor Suppressor Protein / Hypoxia-Inducible Factor 1, alpha Subunit Language: En Journal: Phys Chem Chem Phys Journal subject: BIOFISICA / QUIMICA Year: 2018 Type: Article Affiliation country: China

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