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Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging.
Jian, Xueqiu; Satizabal, Claudia L; Smith, Albert V; Wittfeld, Katharina; Bis, Joshua C; Smith, Jennifer A; Hsu, Fang-Chi; Nho, Kwangsik; Hofer, Edith; Hagenaars, Saskia P; Nyquist, Paul A; Mishra, Aniket; Adams, Hieab H H; Li, Shuo; Teumer, Alexander; Zhao, Wei; Freedman, Barry I; Saba, Yasaman; Yanek, Lisa R; Chauhan, Ganesh; van Buchem, Mark A; Cushman, Mary; Royle, Natalie A; Bryan, R Nick; Niessen, Wiro J; Windham, Beverly G; DeStefano, Anita L; Habes, Mohamad; Heckbert, Susan R; Palmer, Nicholette D; Lewis, Cora E; Eiriksdottir, Gudny; Maillard, Pauline; Mathias, Rasika A; Homuth, Georg; Valdés-Hernández, Maria Del C; Divers, Jasmin; Beiser, Alexa S; Langner, Sönke; Rice, Kenneth M; Bastin, Mark E; Yang, Qiong; Maldjian, Joseph A; Starr, John M; Sidney, Stephen; Risacher, Shannon L; Uitterlinden, André G; Gudnason, Vilmundur G; Nauck, Matthias; Rotter, Jerome I.
Affiliation
  • Jian X; From the Institute of Molecular Medicine, McGovern Medical School at The University of Texas Health Science Center at Houston (M.F., X.J.).
  • Satizabal CL; Department of Neurology, Boston University School of Medicine, MA (C.L.S., S. Seshadri).
  • Smith AV; Icelandic Heart Association, Kópavogur, Iceland (A.V.S., G.E., S. Sigurdsson, V.G.G.).
  • Wittfeld K; German Center for Neurodegenerative Diseases, Site Rostock/Greifswald, Germany (K.W.).
  • Bis JC; Cardiovascular Health Research Unit (B.M.P., J.C.B., S.R.H.).
  • Smith JA; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor (J.A.S., S.L.R.K., W.Z.).
  • Hsu FC; Division of Public Health Sciences (F.-C.H., J.D.).
  • Nho K; Center for Neuroimaging, Indiana University School of Medicine, Indianapolis (K.N., S.L.R.).
  • Hofer E; Department of Neurology (E.H., R.S.).
  • Hagenaars SP; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, United Kingdom (I.J.D., J.M.W., J.M.S., M.d.C.V.-H., M.E.B., N.A.R., S.P.H.).
  • Nyquist PA; Department of Neurology and Neurosurgery (P.A.N., R.F.G.).
  • Mishra A; Bordeaux Population Health Research Centre U1219, Inserm, France (A.M., G.C., S.D.).
  • Adams HHH; Department of Epidemiology (C.M.v.D., H.H.H.A.).
  • Li S; Department of Biostatistics, Boston University School of Public Health, MA (A.S.B., A.L.D., Q.Y., S.L.).
  • Teumer A; Institute for Community Medicine (A.T.).
  • Zhao W; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor (J.A.S., S.L.R.K., W.Z.).
  • Freedman BI; Department of Internal Medicine (B.I.F.).
  • Saba Y; Institute of Molecular Biology and Biochemistry (H.S., Y.S.), Medical University of Graz, Austria.
  • Yanek LR; Department of Medicine (D.M.B., L.R.Y., R.A.M.), Johns Hopkins School of Medicine, Baltimore, MD.
  • Chauhan G; Bordeaux Population Health Research Centre U1219, Inserm, France (A.M., G.C., S.D.).
  • van Buchem MA; Department of Radiology, Leiden University Medical Center, the Netherlands (M.A.v.B.).
  • Cushman M; Department of Medicine, The University of Vermont Larner College of Medicine, Burlington (M.C.).
  • Royle NA; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, United Kingdom (I.J.D., J.M.W., J.M.S., M.d.C.V.-H., M.E.B., N.A.R., S.P.H.).
  • Bryan RN; Department of Diagnostic Medicine, Dell Medical School at The University of Texas at Austin (R.N.B.).
  • Niessen WJ; Departments of Radiology and Medical Informatics (W.J.N.).
  • Windham BG; Department of Medicine, The University of Mississippi School of Medicine, Jackson (W.J.N.).
  • Habes M; Department of Biostatistics, Boston University School of Public Health, MA (A.S.B., A.L.D., Q.Y., S.L.).
  • Heckbert SR; Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia (M.H.).
  • Palmer ND; Cardiovascular Health Research Unit (B.M.P., J.C.B., S.R.H.).
  • Lewis CE; Department of Biochemistry (D.W.B., N.D.P.), Wake Forest School of Medicine, Winston-Salem, NC.
  • Eiriksdottir G; Department of Epidemiology, The University of Alabama at Birmingham School of Public Health (C.E.L.).
  • Maillard P; Icelandic Heart Association, Kópavogur, Iceland (A.V.S., G.E., S. Sigurdsson, V.G.G.).
  • Mathias RA; Department of Neurology, UC Davis School of Medicine (C.S.D., P.M.), CA.
  • Homuth G; Department of Medicine (D.M.B., L.R.Y., R.A.M.), Johns Hopkins School of Medicine, Baltimore, MD.
  • Valdés-Hernández MDC; Institute of Genetics and Functional Genomics, University of Greifswald, Germany (G.H.).
  • Divers J; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, United Kingdom (I.J.D., J.M.W., J.M.S., M.d.C.V.-H., M.E.B., N.A.R., S.P.H.).
  • Beiser AS; Division of Public Health Sciences (F.-C.H., J.D.).
  • Langner S; Department of Biostatistics, Boston University School of Public Health, MA (A.S.B., A.L.D., Q.Y., S.L.).
  • Rice KM; Institute for Diagnostic Radiology and Neuroradiology (S.L.).
  • Bastin ME; Department of Biostatistics, University of Washington School of Public Health, Seattle (K.M.R.).
  • Yang Q; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, United Kingdom (I.J.D., J.M.W., J.M.S., M.d.C.V.-H., M.E.B., N.A.R., S.P.H.).
  • Maldjian JA; Department of Biostatistics, Boston University School of Public Health, MA (A.S.B., A.L.D., Q.Y., S.L.).
  • Starr JM; Department of Radiology, The University of Texas Southwestern Medical Center, Dallas (J.A.M.).
  • Sidney S; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, United Kingdom (I.J.D., J.M.W., J.M.S., M.d.C.V.-H., M.E.B., N.A.R., S.P.H.).
  • Risacher SL; Division of Research, Kaiser Permanente Northern California, Oakland (S. Sidney).
  • Uitterlinden AG; Center for Neuroimaging, Indiana University School of Medicine, Indianapolis (K.N., S.L.R.).
  • Gudnason VG; Departments of Internal Medicine, Epidemiology, and Clinical Chemistry (A.G.U.).
  • Nauck M; Icelandic Heart Association, Kópavogur, Iceland (A.V.S., G.E., S. Sigurdsson, V.G.G.).
  • Rotter JI; Institute for Clinical Chemistry and Laboratory Medicine (M.N.).
Stroke ; 49(8): 1812-1819, 2018 08.
Article in En | MEDLINE | ID: mdl-30002152

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Variation / Brain / Magnetic Resonance Imaging / Mitochondrial Proteins / Exome / White Matter Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Stroke Year: 2018 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Variation / Brain / Magnetic Resonance Imaging / Mitochondrial Proteins / Exome / White Matter Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Stroke Year: 2018 Type: Article