Emerging applications of aptamers for anticoagulation and hemostasis.

Chabata, Charlene V; Frederiksen, James W; Sullenger, Bruce A; Gunaratne, Ruwan

Chabata, Charlene V; Frederiksen, James W; Sullenger, Bruce A; Gunaratne, Ruwan.

Affiliation

Chabata CV; Department of Pharmacology and Cancer Biology.
Frederiksen JW; Department of Surgery.
Sullenger BA; Department of Surgery.
Gunaratne R; Department of Pharmacology and Cancer Biology.

Curr Opin Hematol ; 25(5): 382-388, 2018 09.

Article in En | MEDLINE | ID: mdl-30015643

Subject(s)

Aptamers, Nucleotide/therapeutic use; Factor IXa; Factor Xa Inhibitors/therapeutic use; Hemostasis; Animals; Antidotes/pharmacokinetics; Antidotes/therapeutic use; Aptamers, Nucleotide/adverse effects; Aptamers, Nucleotide/pharmacokinetics; Cardiopulmonary Bypass; Catalytic Domain; Factor IXa/antagonists & inhibitors; Factor IXa/metabolism; Factor Xa Inhibitors/adverse effects; Factor Xa Inhibitors/pharmacokinetics; Hemophilia A/blood; Hemophilia A/drug therapy; Humans; Kallikreins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Factor IXa / Aptamers, Nucleotide / Factor Xa Inhibitors / Hemostasis Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Curr Opin Hematol Journal subject: HEMATOLOGIA Year: 2018 Type: Article

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