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Food-effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers.
Henricks, Linda M; Jacobs, Bart A W; Meulendijks, Didier; Pluim, Dick; van den Broek, Daan; de Vries, Niels; Rosing, Hilde; Beijnen, Jos H; Huitema, Alwin D R; Guchelaar, Henk-Jan; Cats, Annemieke; Schellens, Jan H M.
Affiliation
  • Henricks LM; Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Jacobs BAW; Department of Clinical Pharmacology, Division of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Meulendijks D; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Pluim D; Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • van den Broek D; Department of Clinical Pharmacology, Division of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • de Vries N; Dutch Medicines Evaluation Board (CBG-MEB), Utrecht, The Netherlands.
  • Rosing H; Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Beijnen JH; Department of Clinical Pharmacology, Division of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Huitema ADR; Department of Clinical Chemistry, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Guchelaar HJ; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Cats A; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Schellens JHM; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Br J Clin Pharmacol ; 84(12): 2761-2769, 2018 12.
Article in En | MEDLINE | ID: mdl-30047584
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uracil / Dihydrouracil Dehydrogenase (NADP) Type of study: Clinical_trials Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Br J Clin Pharmacol Year: 2018 Type: Article Affiliation country: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uracil / Dihydrouracil Dehydrogenase (NADP) Type of study: Clinical_trials Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Br J Clin Pharmacol Year: 2018 Type: Article Affiliation country: Netherlands