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Enzyme autoinduction by mitotane supported by population pharmacokinetic modelling in a large cohort of adrenocortical carcinoma patients.
Arshad, U; Taubert, M; Kurlbaum, M; Frechen, S; Herterich, S; Megerle, F; Hamacher, S; Fassnacht, M; Fuhr, U; Kroiss, M.
Affiliation
  • Arshad U; Department I of Pharmacology, University Hospital Cologne, Cologne, Germany.
  • Taubert M; Department I of Pharmacology, University Hospital Cologne, Cologne, Germany.
  • Kurlbaum M; Division of Endocrinology and Diabetology, Department of Internal Medicine I, University Hospital, University of Würzburg, Würzburg, Germany.
  • Frechen S; Department I of Pharmacology, University Hospital Cologne, Cologne, Germany.
  • Herterich S; Clinical Chemistry and Laboratory Medicine, University Hospital Würzburg, Würzburg, Germany.
  • Megerle F; Division of Endocrinology and Diabetology, Department of Internal Medicine I, University Hospital, University of Würzburg, Würzburg, Germany.
  • Hamacher S; Institute of Medical Statistics and Computational Biology, University of Cologne, Cologne, Germany.
  • Fassnacht M; Division of Endocrinology and Diabetology, Department of Internal Medicine I, University Hospital, University of Würzburg, Würzburg, Germany.
  • Fuhr U; Clinical Chemistry and Laboratory Medicine, University Hospital Würzburg, Würzburg, Germany.
  • Kroiss M; Comprehensive Cancer Center Mainfranken, University of Würzburg, Würzburg, Germany.
Eur J Endocrinol ; 179(5): 287-297, 2018 10 16.
Article in En | MEDLINE | ID: mdl-30087117
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adrenal Cortex Neoplasms / Adrenocortical Carcinoma / Antineoplastic Agents, Hormonal / Mitotane / Models, Biological Type of study: Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Eur J Endocrinol Journal subject: ENDOCRINOLOGIA Year: 2018 Type: Article Affiliation country: Germany
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adrenal Cortex Neoplasms / Adrenocortical Carcinoma / Antineoplastic Agents, Hormonal / Mitotane / Models, Biological Type of study: Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Eur J Endocrinol Journal subject: ENDOCRINOLOGIA Year: 2018 Type: Article Affiliation country: Germany