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Genetic and transcriptional evolution alters cancer cell line drug response.
Ben-David, Uri; Siranosian, Benjamin; Ha, Gavin; Tang, Helen; Oren, Yaara; Hinohara, Kunihiko; Strathdee, Craig A; Dempster, Joshua; Lyons, Nicholas J; Burns, Robert; Nag, Anwesha; Kugener, Guillaume; Cimini, Beth; Tsvetkov, Peter; Maruvka, Yosef E; O'Rourke, Ryan; Garrity, Anthony; Tubelli, Andrew A; Bandopadhayay, Pratiti; Tsherniak, Aviad; Vazquez, Francisca; Wong, Bang; Birger, Chet; Ghandi, Mahmoud; Thorner, Aaron R; Bittker, Joshua A; Meyerson, Matthew; Getz, Gad; Beroukhim, Rameen; Golub, Todd R.
Affiliation
  • Ben-David U; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Siranosian B; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Ha G; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Tang H; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Oren Y; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Hinohara K; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Strathdee CA; Harvard Medical School, Boston, MA, USA.
  • Dempster J; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Lyons NJ; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Burns R; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Nag A; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Kugener G; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Cimini B; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Tsvetkov P; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Maruvka YE; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • O'Rourke R; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Garrity A; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Tubelli AA; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Bandopadhayay P; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Tsherniak A; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Vazquez F; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Wong B; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Birger C; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Ghandi M; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Thorner AR; Harvard Medical School, Boston, MA, USA.
  • Bittker JA; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Meyerson M; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Getz G; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Beroukhim R; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Golub TR; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
Nature ; 560(7718): 325-330, 2018 08.
Article in En | MEDLINE | ID: mdl-30089904
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / Genetic Variation / Breast Neoplasms / Evolution, Molecular / Genomic Instability Limits: Humans Language: En Journal: Nature Year: 2018 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / Genetic Variation / Breast Neoplasms / Evolution, Molecular / Genomic Instability Limits: Humans Language: En Journal: Nature Year: 2018 Type: Article Affiliation country: United States