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Clonal heterogeneity influences drug responsiveness in renal cancer assessed by ex vivo drug testing of multiple patient-derived cancer cells.
Saeed, Khalid; Ojamies, Poojitha; Pellinen, Teijo; Eldfors, Samuli; Turkki, Riku; Lundin, Johan; Järvinen, Petrus; Nisen, Harry; Taari, Kimmo; Af Hällström, Taija M; Rannikko, Antti; Mirtti, Tuomas; Kallioniemi, Olli; Östling, Päivi.
Affiliation
  • Saeed K; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Ojamies P; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Pellinen T; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Eldfors S; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Turkki R; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Lundin J; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Järvinen P; Department of Urology, Helsinki University Hospital, Helsinki, Finland.
  • Nisen H; Department of Urology, Helsinki University Hospital, Helsinki, Finland.
  • Taari K; Department of Urology, Helsinki University Hospital, Helsinki, Finland.
  • Af Hällström TM; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Rannikko A; AstraZeneca, Espoo, Finland.
  • Mirtti T; Department of Urology, Helsinki University Hospital, Helsinki, Finland.
  • Kallioniemi O; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Östling P; Department of Pathology, HUSLAB, Helsinki University Hospital, Helsinki, Finland.
Int J Cancer ; 144(6): 1356-1366, 2019 03 15.
Article in En | MEDLINE | ID: mdl-30125350
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Renal Cell / Drug Resistance, Neoplasm / Clonal Evolution / Kidney Neoplasms / Antineoplastic Agents Limits: Adult / Aged / Animals / Humans / Male / Middle aged Language: En Journal: Int J Cancer Year: 2019 Type: Article Affiliation country: Finland
Fulltext
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Renal Cell / Drug Resistance, Neoplasm / Clonal Evolution / Kidney Neoplasms / Antineoplastic Agents Limits: Adult / Aged / Animals / Humans / Male / Middle aged Language: En Journal: Int J Cancer Year: 2019 Type: Article Affiliation country: Finland