Multiple imputation for patient reported outcome measures in randomised controlled trials: advantages and disadvantages of imputing at the item, subscale or composite score level.

Rombach, Ines; Gray, Alastair M; Jenkinson, Crispin; Murray, David W; Rivero-Arias, Oliver

Rombach, Ines; Gray, Alastair M; Jenkinson, Crispin; Murray, David W; Rivero-Arias, Oliver.

Affiliation

Rombach I; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK. ines.rombach@ndorms.ox.ac.uk.
Gray AM; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK. ines.rombach@ndorms.ox.ac.uk.
Jenkinson C; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Murray DW; Health Services Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Rivero-Arias O; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

BMC Med Res Methodol ; 18(1): 87, 2018 08 28.

Article in En | MEDLINE | ID: mdl-30153796

Subject(s)

Outcome Assessment, Health Care/statistics & numerical data; Patient Reported Outcome Measures; Randomized Controlled Trials as Topic/standards; Research Design/standards; Bias; Computer Simulation; Data Interpretation, Statistical; Follow-Up Studies; Humans; Outcome Assessment, Health Care/methods; Outcome Assessment, Health Care/standards; Randomized Controlled Trials as Topic/methods; Randomized Controlled Trials as Topic/statistics & numerical data; Research Design/statistics & numerical data; Sample Size

Key words

Domains; Incomplete data; Missing data; Quality of life (QoL); Questionnaires; Randomised controlled trials (RCTs)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Research Design / Randomized Controlled Trials as Topic / Outcome Assessment, Health Care / Patient Reported Outcome Measures Type of study: Clinical_trials / Guideline / Observational_studies / Prognostic_studies Limits: Humans Language: En Journal: BMC Med Res Methodol Journal subject: MEDICINA Year: 2018 Type: Article Affiliation country: United kingdom

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