The influence of heart failure on the pharmacokinetics of cardiovascular and non-cardiovascular drugs: a critical appraisal of the evidence.

Mangoni, Arduino A; Jarmuzewska, Elzbieta A

Mangoni, Arduino A; Jarmuzewska, Elzbieta A.

Affiliation

Mangoni AA; Discipline of Clinical Pharmacology, College of Medicine and Public Health, Flinders University and Flinders Medical Centre, Adelaide, Australia.
Jarmuzewska EA; Department of Internal Medicine, Polyclinic IRCCS, Ospedale Maggiore, University of Milan, Milan, Italy.

Br J Clin Pharmacol ; 85(1): 20-36, 2019 01.

Article in En | MEDLINE | ID: mdl-30194701

Subject(s)

Cardiovascular Agents/pharmacokinetics; Heart Failure/physiopathology; Area Under Curve; Biological Availability; Cardiac Output/physiology; Comorbidity; Half-Life; Heart/physiopathology; Heart Failure/drug therapy; Heart Failure/epidemiology; Humans; Kidney/physiopathology; Liver/physiopathology; Metabolic Clearance Rate/physiology

Key words

cardiovascular pharmacology; heart failure; pharmacokinetics

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiovascular Agents / Heart Failure Type of study: Prognostic_studies Limits: Humans Language: En Journal: Br J Clin Pharmacol Year: 2019 Type: Article Affiliation country: Australia

Fulltext

XML

PubMed Links

Search on Google