Presenilin 1 Regulates NF-&#954;B Activation via Association with Breakpoint Cluster Region and Casein Kinase II.

Tanaka, Yuki; Sabharwal, Lavannya; Ota, Mitsutoshi; Nakagawa, Ikuma; Jiang, Jing-Jing; Arima, Yasunobu; Ogura, Hideki; Okochi, Masayasu; Ishii, Masaru; Kamimura, Daisuke; Murakami, Masaaki

Presenilin 1 Regulates NF-κB Activation via Association with Breakpoint Cluster Region and Casein Kinase II.

Tanaka, Yuki; Sabharwal, Lavannya; Ota, Mitsutoshi; Nakagawa, Ikuma; Jiang, Jing-Jing; Arima, Yasunobu; Ogura, Hideki; Okochi, Masayasu; Ishii, Masaru; Kamimura, Daisuke; Murakami, Masaaki.

Affiliation

Tanaka Y; Division of Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-0815, Japan.
Sabharwal L; Division of Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-0815, Japan.
Ota M; Division of Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-0815, Japan.
Nakagawa I; Division of Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-0815, Japan.
Jiang JJ; Division of Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-0815, Japan.
Arima Y; Division of Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-0815, Japan.
Ogura H; Division of Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-0815, Japan.
Okochi M; Neuropsychiatry, Department of Integrated Medicine, Division of Internal Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan; and.
Ishii M; Department of Immunology and Cell Biology, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
Kamimura D; Division of Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-0815, Japan; kamimura@igm.hokudai.ac.jp murakami@igm.hokudai.ac.jp.
Murakami M; Division of Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-0815, Japan; kamimura@igm.hokudai.ac.jp murakami@igm.hokudai.ac.jp.

J Immunol ; 201(8): 2256-2263, 2018 10 15.

Article in En | MEDLINE | ID: mdl-30201812

Subject(s)

Alzheimer Disease/genetics; Casein Kinase II/metabolism; Endothelial Cells/physiology; NF-kappa B/metabolism; Presenilin-1/genetics; Proto-Oncogene Proteins c-bcr/metabolism; Amyloid Precursor Protein Secretases/metabolism; Animals; Gene Expression Regulation; Humans; Interleukin-6/genetics; Mice; Mice, Inbred C57BL; NF-kappa B/genetics; Presenilin-1/metabolism; Promoter Regions, Genetic/genetics; Protein Binding; Proto-Oncogene Proteins c-bcr/genetics; RNA, Small Interfering/genetics; Transcription Factor RelA/metabolism; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Endothelial Cells / Casein Kinase II / Proto-Oncogene Proteins c-bcr / Presenilin-1 / Alzheimer Disease Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: J Immunol Year: 2018 Type: Article Affiliation country: Japan

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