Mechanisms of pathogenic effects of eosinophil cationic protein and eosinophil-derived neurotoxin on human keratinocytes.

Amber, Kyle T; Chernyavsky, Alex; Agnoletti, Arianna F; Cozzani, Emanuele; Grando, Sergei A

Amber, Kyle T; Chernyavsky, Alex; Agnoletti, Arianna F; Cozzani, Emanuele; Grando, Sergei A.

Affiliation

Amber KT; Department of Dermatology, University of California Irvine, Irvine, California.
Chernyavsky A; Department of Dermatology, University of Illinois at Chicago, Chicago, IL.
Agnoletti AF; Department of Dermatology, University of California Irvine, Irvine, California.
Cozzani E; Department of Dermatology, University of California Irvine, Irvine, California.
Grando SA; DISSAL Section of Dermatology, San Martino Policlinic Hospital, Genoa, Italy.

Exp Dermatol ; 27(12): 1322-1327, 2018 12.

Article in En | MEDLINE | ID: mdl-30218612

Subject(s)

Eosinophil Cationic Protein/metabolism; Eosinophil-Derived Neurotoxin/metabolism; Eosinophils/metabolism; Keratinocytes/metabolism; Apoptosis; Cell Line; Cell Survival; Chemokine CCL11/metabolism; Chemokine CCL5/metabolism; Eosinophil Cationic Protein/pharmacology; Eosinophil-Derived Neurotoxin/pharmacology; Gene Expression Regulation; Humans; Interleukin-17/metabolism; Interleukin-5/metabolism; Interleukins/metabolism; Keratinocytes/drug effects; Matrix Metalloproteinase 9/metabolism; Reactive Oxygen Species/metabolism

Key words

RANTES; IL-5; eosinophil cationic protein; eosinophil-derived neurotoxin; eotaxin-1; metalloprotease 9

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Keratinocytes / Eosinophil Cationic Protein / Eosinophil-Derived Neurotoxin / Eosinophils Limits: Humans Language: En Journal: Exp Dermatol Journal subject: DERMATOLOGIA Year: 2018 Type: Article

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