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Aiming to Miss a Moving Target: Bromo and Extra Terminal Domain (BET) Selectivity in Constrained ATAD2 Inhibitors.
Bamborough, Paul; Chung, Chun-Wa; Furze, Rebecca C; Grandi, Paola; Michon, Anne-Marie; Watson, Robert J; Mitchell, Darren J; Barnett, Heather; Prinjha, Rab K; Rau, Christina; Sheppard, Robert J; Werner, Thilo; Demont, Emmanuel H.
Affiliation
  • Grandi P; Molecular Discovery Research, Cellzome GmbH , GlaxoSmithKline , Meyerhofstrasse 1 , 69117 Heidelberg , Germany.
  • Michon AM; Molecular Discovery Research, Cellzome GmbH , GlaxoSmithKline , Meyerhofstrasse 1 , 69117 Heidelberg , Germany.
  • Rau C; Molecular Discovery Research, Cellzome GmbH , GlaxoSmithKline , Meyerhofstrasse 1 , 69117 Heidelberg , Germany.
  • Werner T; Molecular Discovery Research, Cellzome GmbH , GlaxoSmithKline , Meyerhofstrasse 1 , 69117 Heidelberg , Germany.
J Med Chem ; 61(18): 8321-8336, 2018 09 27.
Article in En | MEDLINE | ID: mdl-30226378
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Nuclear Proteins / DNA-Binding Proteins / Small Molecule Libraries / Drug Discovery / ATPases Associated with Diverse Cellular Activities Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2018 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Nuclear Proteins / DNA-Binding Proteins / Small Molecule Libraries / Drug Discovery / ATPases Associated with Diverse Cellular Activities Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2018 Type: Article