Pantoprazole Induces Mitochondrial Apoptosis and Attenuates NF-&#954;B Signaling in Glioma Cells.

Geeviman, Khamushavalli; Babu, Deepak; Prakash Babu, Phanithi

Pantoprazole Induces Mitochondrial Apoptosis and Attenuates NF-κB Signaling in Glioma Cells.

Geeviman, Khamushavalli; Babu, Deepak; Prakash Babu, Phanithi.

Affiliation

Geeviman K; Neuroscience Laboratory, Department of Biotechnology and Bioinformatics, School of Life Sciences, University of Hyderabad, F-23/71, Hyderabad, TS, 500 046, India.
Babu D; Neuroscience Laboratory, Department of Biotechnology and Bioinformatics, School of Life Sciences, University of Hyderabad, F-23/71, Hyderabad, TS, 500 046, India.
Prakash Babu P; Neuroscience Laboratory, Department of Biotechnology and Bioinformatics, School of Life Sciences, University of Hyderabad, F-23/71, Hyderabad, TS, 500 046, India. prakash@uohyd.ac.in.

Cell Mol Neurobiol ; 38(8): 1491-1504, 2018 Nov.

Article in En | MEDLINE | ID: mdl-30302629

Subject(s)

Apoptosis/drug effects; Glioma/metabolism; Glioma/pathology; Mitochondria/metabolism; NF-kappa B/metabolism; Pantoprazole/pharmacology; Signal Transduction; Animals; Caspase 3/metabolism; Cell Cycle/drug effects; Cell Line, Tumor; Cell Proliferation/drug effects; Cell Survival/drug effects; Humans; Membrane Potential, Mitochondrial/drug effects; Mitochondria/drug effects; Poly(ADP-ribose) Polymerases/metabolism; Rats; Reactive Oxygen Species/metabolism; Time Factors; Transcription Factor RelA/metabolism; Tumor Necrosis Factor-alpha/pharmacology

Key words

Anticancer; Apoptosis; Glioma; NF-κB signaling; Pantoprazole; V-ATPases

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / NF-kappa B / Apoptosis / Pantoprazole / Glioma / Mitochondria Limits: Animals / Humans Language: En Journal: Cell Mol Neurobiol Year: 2018 Type: Article Affiliation country: India

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