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Information-Derived Mechanistic Hypotheses for Structural Cardiotoxicity.
Svensson, Fredrik; Zoufir, Azedine; Mahmoud, Samar; Afzal, Avid M; Smit, Ines; Giblin, Kathryn A; Clements, Peter J; Mettetal, Jerome T; Pointon, Amy; Harvey, James S; Greene, Nigel; Williams, Richard V; Bender, Andreas.
Affiliation
  • Svensson F; Centre for Molecular Informatics, Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.
  • Zoufir A; Centre for Molecular Informatics, Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.
  • Mahmoud S; Centre for Molecular Informatics, Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.
  • Afzal AM; Centre for Molecular Informatics, Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.
  • Smit I; Centre for Molecular Informatics, Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.
  • Giblin KA; Centre for Molecular Informatics, Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.
  • Clements PJ; GlaxoSmithKline R&D Ltd , Park Road , Ware, Hertfordshire SG12 0DP , United Kingdom.
  • Mettetal JT; Drug Safety and Metabolism , AstraZeneca , 35 Gatehouse Drive , Waltham , Massachusetts 02451 , United States.
  • Pointon A; Safety and ADME Translational Sciences , AstraZeneca , Cambridge Science Park, Milton Road , Cambridge CB4 0WG , United Kingdom.
  • Harvey JS; GlaxoSmithKline R&D Ltd , Park Road , Ware, Hertfordshire SG12 0DP , United Kingdom.
  • Greene N; Predictive Compound Safety and ADME , AstraZeneca , 35 Gatehouse Drive , Waltham , Massachusetts 02451 , United States.
  • Williams RV; Lhasa Limited , Granary Wharf House, 2 Canal Wharf , Leeds LS11 5PS , United Kingdom.
  • Bender A; Centre for Molecular Informatics, Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.
Chem Res Toxicol ; 31(11): 1119-1127, 2018 11 19.
Article in En | MEDLINE | ID: mdl-30350600
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug-Related Side Effects and Adverse Reactions / Heart Diseases / Models, Theoretical Limits: Animals / Humans Country/Region as subject: America do norte Language: En Journal: Chem Res Toxicol Journal subject: TOXICOLOGIA Year: 2018 Type: Article Affiliation country: United kingdom
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug-Related Side Effects and Adverse Reactions / Heart Diseases / Models, Theoretical Limits: Animals / Humans Country/Region as subject: America do norte Language: En Journal: Chem Res Toxicol Journal subject: TOXICOLOGIA Year: 2018 Type: Article Affiliation country: United kingdom