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Parkin deficiency elevates hepatic ischemia/reperfusion injury accompanying decreased mitochondrial autophagy, increased apoptosis, impaired DNA damage repair and altered cell cycle distribution.
Ning, Xiao-Jie; Yan, Xiong; Wang, Yan-Feng; Wang, Ren; Fan, Xiao-Li; Zhong, Zi-Biao; Ye, Qi-Fa.
Affiliation
  • Ning XJ; Hubei Key Laboratory of Medical Technology on Transplantation, Institute of Hepatobiliary Diseases, Zhongnan Hospital of Wuhan University, Transplant Center of Wuhan University, Wuhan, Hubei 430071, P.R. China.
  • Yan X; Hubei Key Laboratory of Medical Technology on Transplantation, Institute of Hepatobiliary Diseases, Zhongnan Hospital of Wuhan University, Transplant Center of Wuhan University, Wuhan, Hubei 430071, P.R. China.
  • Wang YF; Hubei Key Laboratory of Medical Technology on Transplantation, Institute of Hepatobiliary Diseases, Zhongnan Hospital of Wuhan University, Transplant Center of Wuhan University, Wuhan, Hubei 430071, P.R. China.
  • Wang R; Hubei Key Laboratory of Medical Technology on Transplantation, Institute of Hepatobiliary Diseases, Zhongnan Hospital of Wuhan University, Transplant Center of Wuhan University, Wuhan, Hubei 430071, P.R. China.
  • Fan XL; Hubei Key Laboratory of Medical Technology on Transplantation, Institute of Hepatobiliary Diseases, Zhongnan Hospital of Wuhan University, Transplant Center of Wuhan University, Wuhan, Hubei 430071, P.R. China.
  • Zhong ZB; Hubei Key Laboratory of Medical Technology on Transplantation, Institute of Hepatobiliary Diseases, Zhongnan Hospital of Wuhan University, Transplant Center of Wuhan University, Wuhan, Hubei 430071, P.R. China.
  • Ye QF; Hubei Key Laboratory of Medical Technology on Transplantation, Institute of Hepatobiliary Diseases, Zhongnan Hospital of Wuhan University, Transplant Center of Wuhan University, Wuhan, Hubei 430071, P.R. China.
Mol Med Rep ; 18(6): 5663-5668, 2018 Dec.
Article in En | MEDLINE | ID: mdl-30387846
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Reperfusion Injury / Cell Cycle / Apoptosis / Ubiquitin-Protein Ligases / Mitophagy Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Mol Med Rep Year: 2018 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Reperfusion Injury / Cell Cycle / Apoptosis / Ubiquitin-Protein Ligases / Mitophagy Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Mol Med Rep Year: 2018 Type: Article