Dicoumarol Inhibits Multidrug Resistance Protein 1-Mediated Export Processes in Cultured Primary Rat Astrocytes.

Raabe, Janice; Arend, Christian; Steinmeier, Johann; Dringen, Ralf

Raabe, Janice; Arend, Christian; Steinmeier, Johann; Dringen, Ralf.

Affiliation

Raabe J; Centre for Biomolecular Interactions Bremen, Faculty 2 (Biology/Chemistry), University of Bremen, P.O. Box 330440, 28334, Bremen, Germany.
Arend C; Centre for Biomolecular Interactions Bremen, Faculty 2 (Biology/Chemistry), University of Bremen, P.O. Box 330440, 28334, Bremen, Germany.
Steinmeier J; Centre for Environmental Research and Sustainable Technology, University of Bremen, Bremen, Germany.
Dringen R; Centre for Biomolecular Interactions Bremen, Faculty 2 (Biology/Chemistry), University of Bremen, P.O. Box 330440, 28334, Bremen, Germany.

Neurochem Res ; 44(2): 333-346, 2019 Feb.

Article in En | MEDLINE | ID: mdl-30443714

Subject(s)

ATP Binding Cassette Transporter, Subfamily B, Member 1/drug effects; Astrocytes/drug effects; Cell Survival/drug effects; Dicumarol/pharmacology; Propionates/pharmacology; Quinolines/pharmacology; ATP Binding Cassette Transporter, Subfamily B/drug effects; Animals; Animals, Newborn; Astrocytes/metabolism; Cells, Cultured; Glutathione/metabolism; Hydrogen Peroxide/metabolism; Rats, Wistar

Key words

Astrocytes; Drug export; GSSG; Glutathione; Mrp; NQO1

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propionates / Quinolines / Dicumarol / Cell Survival / Astrocytes / ATP Binding Cassette Transporter, Subfamily B, Member 1 Limits: Animals Language: En Journal: Neurochem Res Year: 2019 Type: Article Affiliation country: Germany

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