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Low expression of PDK1 inhibits renal cell carcinoma cell proliferation, migration, invasion and epithelial mesenchymal transition through inhibition of the PI3K-PDK1-Akt pathway.
Zhou, Wei-Min; Wu, Gao-Liang; Huang, Ji; Li, Jin-Gao; Hao, Chao; He, Qiu-Ming; Chen, Xiao-Dan; Wang, Gong-Xian; Tu, Xin-Hua.
Affiliation
  • Zhou WM; Jiangxi Medical College, Nanchang University, Nanchang 330006, PR China; Department of Urology, Jiangxi Cancer Hospital, Nanchang 330029, PR China.
  • Wu GL; Department of Urology, Jiangxi Cancer Hospital, Nanchang 330029, PR China.
  • Huang J; Department of Urology, Jiangxi Cancer Hospital, Nanchang 330029, PR China.
  • Li JG; Department of Radiotherapy, Jiangxi Cancer Hospital, Nanchang 330029, PR China.
  • Hao C; Department of Urology, Jiangxi Cancer Hospital, Nanchang 330029, PR China.
  • He QM; Department of Urology, Jiangxi Cancer Hospital, Nanchang 330029, PR China.
  • Chen XD; Department of Science and Education, Jiangxi Cancer Hospital, Nanchang 330029, PR China.
  • Wang GX; Jiangxi Medical College, Nanchang University, Nanchang 330006, PR China; Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, PR China. Electronic address: gongxianwang118@163.com.
  • Tu XH; Department of Urology, Jiangxi Cancer Hospital, Nanchang 330029, PR China. Electronic address: tu_xinhua@126.com.
Cell Signal ; 56: 1-14, 2019 04.
Article in En | MEDLINE | ID: mdl-30465826
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Renal Cell / Cell Movement / Cell Proliferation / Epithelial-Mesenchymal Transition / 3-Phosphoinositide-Dependent Protein Kinases / Kidney Neoplasms Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Cell Signal Year: 2019 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Renal Cell / Cell Movement / Cell Proliferation / Epithelial-Mesenchymal Transition / 3-Phosphoinositide-Dependent Protein Kinases / Kidney Neoplasms Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Cell Signal Year: 2019 Type: Article