Elevated mRNA Levels of AURKA, CDC20 and TPX2 are associated with poor prognosis of smoking related lung adenocarcinoma using bioinformatics analysis.

Zhang, Meng-Yu; Liu, Xiao-Xia; Li, Hao; Li, Rui; Liu, Xiao; Qu, Yi-Qing

Zhang, Meng-Yu; Liu, Xiao-Xia; Li, Hao; Li, Rui; Liu, Xiao; Qu, Yi-Qing.

Affiliation

Zhang MY; Department of Respiratory Medicine, Qilu Hospital of Shandong University, Jinan 250012, China.
Liu XX; Department of Respiratory Medicine, Qilu Hospital of Shandong University, Jinan 250012, China.
Li H; Department of Respiratory Medicine, Qilu Hospital of Shandong University, Jinan 250012, China.
Li R; Department of Respiratory Medicine, Qilu Hospital of Shandong University, Jinan 250012, China.
Liu X; Department of Respiratory Medicine, Qilu Hospital of Shandong University, Jinan 250012, China.
Qu YQ; Department of Respiratory Medicine, Qilu Hospital of Shandong University, Jinan 250012, China.

Int J Med Sci ; 15(14): 1676-1685, 2018.

Article in En | MEDLINE | ID: mdl-30588191

Subject(s)

Adenocarcinoma of Lung/pathology; Aurora Kinase A/analysis; Biomarkers, Tumor/analysis; Cdc20 Proteins/analysis; Cell Cycle Proteins/analysis; Lung Neoplasms/pathology; Microtubule-Associated Proteins/analysis; Nuclear Proteins/analysis; Adenocarcinoma of Lung/etiology; Adenocarcinoma of Lung/genetics; Adenocarcinoma of Lung/mortality; Aged; Aurora Kinase A/genetics; Biomarkers, Tumor/genetics; Cdc20 Proteins/genetics; Cell Cycle Proteins/genetics; Computational Biology; Datasets as Topic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Lung Neoplasms/etiology; Lung Neoplasms/genetics; Lung Neoplasms/mortality; Male; Microtubule-Associated Proteins/genetics; Middle Aged; Nuclear Proteins/genetics; Prognosis; RNA, Messenger/analysis; Smoking/adverse effects; Transcriptome/genetics

Key words

Kaplan-Meier analysis; biomarkers; differentially expressed genes; gene ontology; lung adenocarcinoma

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Biomarkers, Tumor / Cell Cycle Proteins / Cdc20 Proteins / Aurora Kinase A / Adenocarcinoma of Lung / Lung Neoplasms / Microtubule-Associated Proteins Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Int J Med Sci Journal subject: MEDICINA Year: 2018 Type: Article Affiliation country: China

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