Synthesis of an Anti-hepatitis B Agent, 2'-Fluoro-6'-methylene-carbocyclic Adenosine (FMCA) and Its Phosphoramidate (FMCAP).

Singh, Uma S; Mulamoottil, Varughese A; Chu, Chung K

Singh, Uma S; Mulamoottil, Varughese A; Chu, Chung K.

Affiliation

Singh US; The University of Georgia , College of Pharmacy , Athens , Georgia 30602 , United States.
Mulamoottil VA; The University of Georgia , College of Pharmacy , Athens , Georgia 30602 , United States.
Chu CK; The University of Georgia , College of Pharmacy , Athens , Georgia 30602 , United States.

J Org Chem ; 84(2): 752-759, 2019 01 18.

Article in En | MEDLINE | ID: mdl-30589264

Subject(s)

Adenosine/analogs & derivatives; Amides/chemical synthesis; Antiviral Agents/chemical synthesis; Phosphoric Acids/chemical synthesis; Adenosine/chemical synthesis; Adenosine/chemistry; Adenosine/pharmacology; Amides/chemistry; Amides/pharmacology; Antiviral Agents/chemistry; Antiviral Agents/pharmacology; Hepatitis B virus/drug effects; Molecular Conformation; Phosphoric Acids/chemistry; Phosphoric Acids/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Phosphoric Acids / Adenosine / Amides Language: En Journal: J Org Chem Year: 2019 Type: Article Affiliation country: United States

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