NK Cells Activated through Antibody-Dependent Cell Cytotoxicity and Armed with Degranulation/IFN-Î³ Production Suppress Antibody-dependent Enhancement of Dengue Viral Infection.

Sun, Peifang; Williams, Maya; Nagabhushana, Nishith; Jani, Vihasi; Defang, Gabriel; Morrison, Brian J

Sun, Peifang; Williams, Maya; Nagabhushana, Nishith; Jani, Vihasi; Defang, Gabriel; Morrison, Brian J.

Affiliation

Sun P; Henry Jackson Foundation, Bethesda, MD, USA. peifang.sun2.ctr@mail.mil.
Williams M; Viral and Rickettsial Diseases Department, Infectious Diseases Directorate, Naval Medical Research Center, Silver Spring, MD, USA.
Nagabhushana N; Henry Jackson Foundation, Bethesda, MD, USA.
Jani V; Henry Jackson Foundation, Bethesda, MD, USA.
Defang G; Viral and Rickettsial Diseases Department, Infectious Diseases Directorate, Naval Medical Research Center, Silver Spring, MD, USA.
Morrison BJ; Viral and Rickettsial Diseases Department, Infectious Diseases Directorate, Naval Medical Research Center, Silver Spring, MD, USA.

Sci Rep ; 9(1): 1109, 2019 02 01.

Article in En | MEDLINE | ID: mdl-30710094

Subject(s)

Dengue Virus/physiology; Dengue/immunology; Killer Cells, Natural/immunology; Antibodies, Viral/metabolism; Antibody-Dependent Cell Cytotoxicity; Antibody-Dependent Enhancement; Antigen Presentation; Cell Degranulation; Cells, Cultured; Cross Reactions; Humans; Immune Sera; Immunomodulation; Interferon-gamma/metabolism; Lymphocyte Activation; Lymphocyte Depletion; Virus Replication

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Killer Cells, Natural / Dengue / Dengue Virus Limits: Humans Language: En Journal: Sci Rep Year: 2019 Type: Article Affiliation country: United States

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