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NADP+ is an endogenous PARP inhibitor in DNA damage response and tumor suppression.
Bian, Chunjing; Zhang, Chao; Luo, Tao; Vyas, Aditi; Chen, Shih-Hsun; Liu, Chao; Kassab, Muzaffer Ahmad; Yang, Ying; Kong, Mei; Yu, Xiaochun.
Affiliation
  • Bian C; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA.
  • Zhang C; Department of General Surgery of Xuanwu Hospital, Capital Medical University, 100053, Beijing, China.
  • Luo T; Vascular Surgery Department of Xuanwu Hospital, Institute of Vascular Surgery, Capital Medical University, 100053, Beijing, China.
  • Vyas A; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA.
  • Chen SH; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA.
  • Liu C; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA.
  • Kassab MA; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA.
  • Yang Y; Department of Cancer Biology, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA.
  • Kong M; Department of Cancer Biology, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA.
  • Yu X; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA. xyu@coh.org.
Nat Commun ; 10(1): 693, 2019 02 11.
Article in En | MEDLINE | ID: mdl-30741937
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Poly(ADP-ribose) Polymerases / Poly(ADP-ribose) Polymerase Inhibitors / NADP / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Poly(ADP-ribose) Polymerases / Poly(ADP-ribose) Polymerase Inhibitors / NADP / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Type: Article Affiliation country: United States