Recruitment of central angiotensin II type 1 receptor associated neurocircuits in carbon dioxide associated fear.

Winter, Andrew; Ahlbrand, Rebecca; Sah, Renu

Winter, Andrew; Ahlbrand, Rebecca; Sah, Renu.

Affiliation

Winter A; Dept. of Pharmacology and Systems Physiology, University of Cincinnati, United States; Neuroscience Graduate Program, University of Cincinnati, United States.
Ahlbrand R; Dept. of Pharmacology and Systems Physiology, University of Cincinnati, United States; VA Medical Center, Cincinnati, OH, 45221, United States.
Sah R; Dept. of Pharmacology and Systems Physiology, University of Cincinnati, United States; Neuroscience Graduate Program, University of Cincinnati, United States; VA Medical Center, Cincinnati, OH, 45221, United States. Electronic address: sahr@uc.edu.

Prog Neuropsychopharmacol Biol Psychiatry ; 92: 378-386, 2019 06 08.

Article in En | MEDLINE | ID: mdl-30776402

Subject(s)

Carbon Dioxide/metabolism; Fear/physiology; Neural Pathways/physiology; Receptor, Angiotensin, Type 1/physiology; Angiotensin II Type 1 Receptor Blockers/pharmacology; Angiotensin-Converting Enzyme Inhibitors/metabolism; Animals; Brain/physiology; Freezing Reaction, Cataleptic/drug effects; Homeostasis/physiology; Infusions, Intraventricular; Losartan/pharmacology; Male; Mice; Paraventricular Hypothalamic Nucleus/metabolism; Receptor, Angiotensin, Type 1/metabolism; Subfornical Organ/metabolism; Up-Regulation

Key words

Angiotensin II type 1 receptor (AT1R); Carbon dioxide (CO(2)); Fear; Losartan; PTSD; Panic disorder

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carbon Dioxide / Receptor, Angiotensin, Type 1 / Fear / Neural Pathways Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Prog Neuropsychopharmacol Biol Psychiatry Year: 2019 Type: Article Affiliation country: United States

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