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MiR-33a is a therapeutic target in SPG4-related hereditary spastic paraplegia human neurons.
Nakazeki, Fumiko; Tsuge, Itaru; Horie, Takahiro; Imamura, Keiko; Tsukita, Kayoko; Hotta, Akitsu; Baba, Osamu; Kuwabara, Yasuhide; Nishino, Tomohiro; Nakao, Tetsushi; Nishiga, Masataka; Nishi, Hitoo; Nakashima, Yasuhiro; Ide, Yuya; Koyama, Satoshi; Kimura, Masahiro; Tsuji, Shuhei; Naitoh, Motoko; Suzuki, Shigehiko; Izumi, Yuishin; Kawarai, Toshitaka; Kaji, Ryuji; Kimura, Takeshi; Inoue, Haruhisa; Ono, Koh.
Affiliation
  • Nakazeki F; Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Tsuge I; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
  • Horie T; Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Imamura K; Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Tsukita K; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
  • Hotta A; iPSC-based Drug Discovery and Development Team, RIKEN BioResource Center (RIKEN BRC), Kyoto, Japan.
  • Baba O; Medical-risk Avoidance based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (RIKEN AIP), Kyoto, Japan.
  • Kuwabara Y; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
  • Nishino T; iPSC-based Drug Discovery and Development Team, RIKEN BioResource Center (RIKEN BRC), Kyoto, Japan.
  • Nakao T; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
  • Nishiga M; Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Nishi H; Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Nakashima Y; Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Ide Y; Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Koyama S; Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Kimura M; Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Tsuji S; Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Naitoh M; Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Suzuki S; Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Izumi Y; Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Kawarai T; Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Kaji R; Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Kimura T; Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Inoue H; Department of Clinical Neuroscience, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
  • Ono K; Department of Clinical Neuroscience, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
Clin Sci (Lond) ; 133(4): 583-595, 2019 02 28.
Article in En | MEDLINE | ID: mdl-30777884
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligonucleotides / Genetic Therapy / Spastic Paraplegia, Hereditary / Neurites / MicroRNAs / Induced Pluripotent Stem Cells / Neural Stem Cells / Spastin Limits: Humans Language: En Journal: Clin Sci (Lond) Year: 2019 Type: Article Affiliation country: Japan
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligonucleotides / Genetic Therapy / Spastic Paraplegia, Hereditary / Neurites / MicroRNAs / Induced Pluripotent Stem Cells / Neural Stem Cells / Spastin Limits: Humans Language: En Journal: Clin Sci (Lond) Year: 2019 Type: Article Affiliation country: Japan