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Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline.
Blaser, Adrian; Sutherland, Hamish S; Tong, Amy S T; Choi, Peter J; Conole, Daniel; Franzblau, Scott G; Cooper, Christopher B; Upton, Anna M; Lotlikar, Manisha; Denny, William A; Palmer, Brian D.
Affiliation
  • Blaser A; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Sutherland HS; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Tong AST; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Choi PJ; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Conole D; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Franzblau SG; Institute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA.
  • Cooper CB; Global Alliance for TB Drug Development, 40 Wall Street, NY 10005, USA.
  • Upton AM; Global Alliance for TB Drug Development, 40 Wall Street, NY 10005, USA.
  • Lotlikar M; Global Alliance for TB Drug Development, 40 Wall Street, NY 10005, USA.
  • Denny WA; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand; Maurice Wilkins Centre, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. Electronic address: b.denny@auckland.ac.nz.
  • Palmer BD; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand; Maurice Wilkins Centre, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Bioorg Med Chem ; 27(7): 1283-1291, 2019 04 01.
Article in En | MEDLINE | ID: mdl-30792104

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Potassium Channel Blockers / Ether-A-Go-Go Potassium Channels / Diarylquinolines / Mycobacterium tuberculosis / Antitubercular Agents Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2019 Type: Article Affiliation country: New Zealand

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Potassium Channel Blockers / Ether-A-Go-Go Potassium Channels / Diarylquinolines / Mycobacterium tuberculosis / Antitubercular Agents Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2019 Type: Article Affiliation country: New Zealand